Silybin


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769 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 35
2 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 29
3 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 25
4 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 24
5 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 24
6 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 22
7 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 21
8 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 20
9 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 18
10 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 17
11 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 15
12 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 15
13 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 15
14 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 14
15 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 14
16 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 13
17 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 13
18 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 13
19 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 13
20 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 13
21 nitric oxide synthase 2, inducible NOS2_MOUSE Nos2 Mus musculus 18126 2585 12
22 cyclin dependent kinase inhibitor 1A CDN1A_HUMAN CDKN1A Homo sapiens 1026 1631 12
23 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 12
24 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 12
25 caspase 9 CASP9_HUMAN CASP9 Homo sapiens 842 1801 11
26 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 11
27 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 11
28 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 10
29 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 10
30 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 10
31 cyclin dependent kinase inhibitor 1B CDN1B_HUMAN CDKN1B Homo sapiens 1027 588 10
32 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 10
33 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 10
34 interferon alpha inducible protein 27 IFI27_HUMAN IFI27 Homo sapiens 3429 662 10
35 cyclin dependent kinase 2 CDK2_HUMAN CDK2 Homo sapiens 1017 1201 9
36 prostaglandin-endoperoxide synthase 2 PGH2_MOUSE Ptgs2 Mus musculus 19225 1538 9
37 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 9
38 cyclin dependent kinase 4 CDK4_HUMAN CDK4 Homo sapiens 1019 868 9
39 vimentin VIME_HUMAN VIM Homo sapiens 7431 1102 9
40 cyclin dependent kinase 1 CDK1_HUMAN CDK1 Homo sapiens 983 1023 8
41 cadherin 1 CADH1_HUMAN CDH1 Homo sapiens 999 1360 8
42 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 7
43 matrix metallopeptidase 9 MMP9_MOUSE Mmp9 Mus musculus 17395 1156 7
44 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 7
45 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 7
46 cytochrome c oxidase II, mitochondrial COX2_MOUSE COX2 Mus musculus 17709 1349 7
47 cyclin D1 CCND1_MOUSE Ccnd1 Mus musculus 12443 585 7
48 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 7
49 cyclin B1 CCNB1_HUMAN CCNB1 Homo sapiens 891 652 7
50 v-rel reticuloendotheliosis viral oncogene homolog A (avian) TF65_MOUSE Rela Mus musculus 19697 993 7