Protein Name cyclin dependent kinase 2
Organism Homo sapiens
Gene ID 1017
Gene Symbol


UniProt P24941 (CDK2_HUMAN), G3V5T9 (G3V5T9_HUMAN), A0A024RB10 (A0A024RB10_HUMAN), E7ESI2 (E7ESI2_HUMAN), A0A024RB77 (A0A024RB77_HUMAN), B4DDL9 (B4DDL9_HUMAN)
Relationships Total Number of functionally related compound(s) : 1201
Total Number of Articles : 1821

cyclin dependent kinase 2

Gene Summary

This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]

  • cyclin-dependent kinase 2
  • cdc2-related protein kinase
  • cell division protein kinase 2
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