Protein Name | cyclin dependent kinase 2 |
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Organism | Homo sapiens |
Gene ID | 1017 |
Gene Symbol | CDK2 |
UniProt | P24941 (CDK2_HUMAN), G3V5T9 (G3V5T9_HUMAN), A0A024RB10 (A0A024RB10_HUMAN), E7ESI2 (E7ESI2_HUMAN), A0A024RB77 (A0A024RB77_HUMAN), B4DDL9 (B4DDL9_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
1201
Total Number of Articles : 1821 |
Description |
cyclin dependent kinase 2 |
Gene Summary |
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
synonyms |
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Properties | |