Protein Name vimentin
Organism Homo sapiens
Gene ID 7431
Gene Symbol


UniProt P08670 (VIME_HUMAN), V9HWE1 (V9HWE1_HUMAN)
Relationships Total Number of functionally related compound(s) : 1102
Total Number of Articles : 1642


Gene Summary

This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]

  • vimentin
  • epididymis secretory sperm binding protein
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