NVP-BKM120


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140 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 26
2 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_HUMAN PIK3CA Homo sapiens 5290 683 16
3 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 14
4 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 13
5 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 10
6 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 8
7 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 6
8 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 6
9 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta PK3CD_HUMAN PIK3CD Homo sapiens 5293 775 5
10 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 5
11 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 5
12 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 5
13 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 5
14 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 4
15 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha PK3CA_MOUSE Pik3ca Mus musculus 18706 131 4
16 mechanistic target of rapamycin kinase MTOR_MOUSE Mtor Mus musculus 56717 1120 4
17 RAD51 recombinase RAD51_HUMAN RAD51 Homo sapiens 5888 537 3
18 transformation related protein 53, pseudogene - Trp53-ps Mus musculus 22060 1552 3
19 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 3
20 H3 histone pseudogene 16 - H3P16 Homo sapiens 644914 2095 3
21 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 3
22 CREB regulated transcription coactivator 1 CRTC1_MOUSE Crtc1 Mus musculus 382056 993 3
23 erb-b2 receptor tyrosine kinase 2 ERBB2_MOUSE Erbb2 Mus musculus 13866 567 3
24 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 3
25 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 3
26 caspase 3 CASP3_MOUSE Casp3 Mus musculus 12367 1791 2
27 insulin receptor substrate 1 IRS1_HUMAN IRS1 Homo sapiens 3667 493 2
28 forkhead box O3 FOXO3_HUMAN FOXO3 Homo sapiens 2309 544 2
29 breast cancer 1, early onset BRCA1_MOUSE Brca1 Mus musculus 12189 100 2
30 C-X-C motif chemokine receptor 4 CXCR4_HUMAN CXCR4 Homo sapiens 7852 1170 2
31 BCL2 like 1 B2CL1_HUMAN BCL2L1 Homo sapiens 598 1360 2
32 nuclear receptor subfamily 4 group A member 1 NR4A1_HUMAN NR4A1 Homo sapiens 3164 657 2
33 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 2
34 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 2
35 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 2
36 CREB regulated transcription coactivator 2 CRTC2_MOUSE Crtc2 Mus musculus 74343 347 2
37 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 2
38 ribosomal protein S6 kinase B1 KS6B1_HUMAN RPS6KB1 Homo sapiens 6198 764 2
39 collagen type XI alpha 2 chain COBA2_HUMAN COL11A2 Homo sapiens 1302 794 2
40 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 2
41 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 2
42 telomerase reverse transcriptase TERT_HUMAN TERT Homo sapiens 7015 997 2
43 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 2
44 annexin A5 ANXA5_HUMAN ANXA5 Homo sapiens 308 1785 2
45 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 2
46 sirtuin 1 SIR1_HUMAN SIRT1 Homo sapiens 23411 1253 1
47 interleukin 6 receptor IL6RA_HUMAN IL6R Homo sapiens 3570 248 1
48 aldo-keto reductase family 1 member C3 AK1C3_HUMAN AKR1C3 Homo sapiens 8644 408 1
49 forkhead box M1 FOXM1_HUMAN FOXM1 Homo sapiens 2305 352 1
50 BCL2 antagonist/killer 1 BAK_HUMAN BAK1 Homo sapiens 578 490 1