7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine


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58 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 eukaryotic translation initiation factor 2 alpha kinase 3 E2AK3_HUMAN EIF2AK3 Homo sapiens 9451 737 40
2 eukaryotic translation initiation factor 2 alpha kinase 3 E2AK3_MOUSE Eif2ak3 Mus musculus 13666 348 18
3 eukaryotic translation initiation factor 2A EIF2A_HUMAN EIF2A Homo sapiens 83939 566 10
4 eukaryotic translation initiation factor 2A EIF2A_MOUSE Eif2a Mus musculus 229317 215 6
5 activating transcription factor 4 ATF4_RAT Atf4 Rattus norvegicus 79255 138 5
6 eukaryotic translation initiation factor 2A D3ZUV3_RAT Eif2a Rattus norvegicus 502531 185 4
7 activating transcription factor 4 ATF4_MOUSE Atf4 Mus musculus 11911 213 4
8 DNA-damage inducible transcript 3 DDIT3_MOUSE Ddit3 Mus musculus 13198 383 3
9 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 2
10 heat shock protein 5 BIP_MOUSE Hspa5 Mus musculus 14828 360 2
11 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 2
12 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 2
13 activating transcription factor 4 ATF4_HUMAN ATF4 Homo sapiens 468 451 2
14 DNA-damage inducible transcript 3 Q496Y7_RAT Ddit3 Rattus norvegicus 29467 340 2
15 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 2
16 PYD and CARD domain containing ASC_HUMAN PYCARD Homo sapiens 29108 809 1
17 eukaryotic translation initiation factor 2A G1TAW7_RABIT EIF2A Oryctolagus cuniculus 100338417 51 1
18 TNF superfamily member 11 TNF11_HUMAN TNFSF11 Homo sapiens 8600 766 1
19 tyrosine aminotransferase ATTY_MOUSE Tat Mus musculus 234724 140 1
20 caspase 3 CASP3_MOUSE Casp3 Mus musculus 12367 1791 1
21 parkin PRKN_DROME park Drosophila melanogaster 40336 42 1
22 cell division cycle 25C MPIP3_HUMAN CDC25C Homo sapiens 995 386 1
23 KIT proto-oncogene, receptor tyrosine kinase KIT_HUMAN KIT Homo sapiens 3815 679 1
24 ankyrin repeat, SAM and basic leucine zipper domain containing 1 ASZ1_HUMAN ASZ1 Homo sapiens 136991 81 1
25 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 1
26 signal transducer and activator of transcription 3 STAT3_RAT Stat3 Rattus norvegicus 25125 689 1
27 B cell leukemia/lymphoma 2 BCL2_MOUSE Bcl2 Mus musculus 12043 1497 1
28 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 1
29 nuclear factor, erythroid derived 2, like 2 NF2L2_MOUSE Nfe2l2 Mus musculus 18024 2012 1
30 tumor necrosis factor (ligand) superfamily, member 11 TNF11_MOUSE Tnfsf11 Mus musculus 21943 974 1
31 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 1
32 Janus kinase 2 JAK2_RAT Jak2 Rattus norvegicus 24514 336 1
33 ras homolog family member A RHOA_MOUSE Rhoa Mus musculus 11848 337 1
34 adiponectin, C1Q and collagen domain containing ADIPO_HUMAN ADIPOQ Homo sapiens 9370 1074 1
35 synaptojanin 1 SYNJ1_HUMAN SYNJ1 Homo sapiens 8867 28 1
36 BCL2 associated X, apoptosis regulator G3V8T9_RAT Bax Rattus norvegicus 24887 1472 1
37 BCL2, apoptosis regulator BCL2_RAT Bcl2 Rattus norvegicus 24224 1676 1
38 forkhead box O3 FOXO3_HUMAN FOXO3 Homo sapiens 2309 544 1
39 BCL2-associated X protein BAX_MOUSE Bax Mus musculus 12028 1197 1
40 hes family bHLH transcription factor 1 HES1_MOUSE Hes1 Mus musculus 15205 106 1
41 eukaryotic translation initiation factor 2 alpha kinase 4 E2AK4_HUMAN EIF2AK4 Homo sapiens 440275 96 1
42 rolled ERKA_DROME rl Drosophila melanogaster 3354888 63 1
43 PTEN-induced putative kinase 1 PINK1_DROME Pink1 Drosophila melanogaster 31607 34 1
44 caspase 12 CASPC_RAT Casp12 Rattus norvegicus 156117 186 1
45 glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) LFG1_MOUSE Grina Mus musculus 66168 4 1
46 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 1
47 LOW QUALITY PROTEIN: caspase-12 - LOC103350677 Oryctolagus cuniculus 103350677 7 1
48 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 1
49 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 1
50 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 1