| Protein Name | caspase 12 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 156117 |
| Gene Symbol | Casp12 |
| UniProt | Q920D5 (CASPC_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
186
Total Number of Articles : 239 |
Description |
caspase 12 |
| Gene Summary |
Enables cysteine-type peptidase activity; endopeptidase activity; and protease binding activity. Involved in several processes, including cellular response to manganese ion; positive regulation of striated muscle cell apoptotic process; and protein autoprocessing. Located in cytosol and nucleus. Used to study sciatic neuropathy. Biomarker of several diseases, including diabetes mellitus (multiple); heart disease (multiple); neurodegenerative disease (multiple); post-traumatic stress disorder; and ureteral obstruction. Orthologous to human CASP12 (caspase 12 (gene/pseudogene)). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |