| 1 |
34951995 | BZW1 Facilitates Glycolysis and Promotes Tumor Growth in Pancreatic Ductal Adenocarcinoma Through Potentiating eIF2α Phosphorylation. | 2022 Apr |
1 |
| 2 |
35181617 | Melatonin Induces AGS Gastric Cancer Cell Apoptosis via Regulating PERK/eIF2α and HSF1/NF-κB Signaling Pathway. | 2022 Jan |
2 |
| 3 |
35435728 | Chlamydia psittaci Induces Autophagy in Human Bronchial Epithelial Cells via PERK and IRE1α, but Not ATF6 Pathway. | 2022 May 19 |
1 |
| 4 |
33360915 | Porcine epidemic diarrhea virus infections induce autophagy in Vero cells via ROS-dependent endoplasmic reticulum stress through PERK and IRE1 pathways. | 2021 Feb |
1 |
| 5 |
33594322 | Possible mechanisms of the PERK pathway on neuronal apoptosis in a rat model of surgical brain injury. | 2021 |
2 |
| 6 |
34052329 | PERK-eIF2α-ERK1/2 axis drives mesenchymal-endothelial transition of cancer-associated fibroblasts in pancreatic cancer. | 2021 Sep 1 |
1 |
| 7 |
34106769 | Zika Virus Induces an Atypical Tripartite Unfolded Protein Response with Sustained Sensor and Transient Effector Activation and a Blunted BiP Response. | 2021 Jun 30 |
1 |
| 8 |
34195069 | The Novel Curcumin Derivative 1g Induces Mitochondrial and ER-Stress-Dependent Apoptosis in Colon Cancer Cells by Induction of ROS Production. | 2021 |
1 |
| 9 |
34408924 | IFN-γ-induced ER stress impairs autophagy and triggers apoptosis in lung cancer cells. | 2021 |
1 |
| 10 |
34650437 | Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway. | 2021 |
2 |
| 11 |
31891755 | Involvement of PERK-CHOP pathway in fumonisin B1- induced cytotoxicity in human gastric epithelial cells. | 2020 Feb |
1 |
| 12 |
32615282 | Reciprocal regulation between GCN2 (eIF2AK4) and PERK (eIF2AK3) through the JNK-FOXO3 axis to modulate cancer drug resistance and clonal survival. | 2020 Sep 15 |
1 |
| 13 |
33028016 | Characterization of a PERK Kinase Inhibitor with Anti-Myeloma Activity. | 2020 Oct 5 |
1 |
| 14 |
33042407 | Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux. | 2020 |
1 |
| 15 |
33137417 | Adiponectin protects HL-1 cardiomyocytes against rotenone-induced cytotoxicity through AMPK activation. | 2020 Dec 15 |
1 |
| 16 |
30448406 | Role of Endoplasmic Reticulum Stress in Proinflammatory Cytokine-Mediated Inhibition of Trophoblast Invasion in Placenta-Related Complications of Pregnancy. | 2019 Feb |
1 |
| 17 |
30651358 | Porcine Circovirus Type 2 Induces ORF3-Independent Mitochondrial Apoptosis via PERK Activation and Elevation of Cytosolic Calcium. | 2019 Apr 1 |
1 |
| 18 |
30704503 | CYT997(Lexibulin) induces apoptosis and autophagy through the activation of mutually reinforced ER stress and ROS in osteosarcoma. | 2019 Jan 31 |
1 |
| 19 |
30810108 | [Niskocząsteczkowe inhibitory szlaku adaptacyjnej odpowiedzi na stres zależnego od kinazy PERK jako nowatorska strategia terapeutyczna w leczeniu choroby Alzheimera]. | 2019 Jan 28 |
1 |
| 20 |
30931942 | The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors. | 2019 Apr 1 |
2 |
| 21 |
31199053 | Pro-apoptotic effect of haem oxygenase-1 in human colorectal carcinoma cells via endoplasmic reticular stress. | 2019 Aug |
3 |
| 22 |
31312024 | Regulation of PERK expression by FOXO3: a vulnerability of drug-resistant cancer cells. | 2019 Sep |
1 |
| 23 |
31316342 | PERK-Mediated Unfolded Protein Response Activation and Oxidative Stress in PARK20 Fibroblasts. | 2019 |
2 |
| 24 |
31396081 | Liraglutide Increases VEGF Expression via CNPY2-PERK Pathway Induced by Hypoxia/Reoxygenation Injury. | 2019 |
1 |
| 25 |
31767864 | Knockdown of cytokeratin 8 overcomes chemoresistance of chordoma cells by aggravating endoplasmic reticulum stress through PERK/eIF2α arm of unfolded protein response and blocking autophagy. | 2019 Nov 25 |
2 |
| 26 |
31906029 | Activation of PERK Contributes to Apoptosis and G2/M Arrest by Microtubule Disruptors in Human Colorectal Carcinoma Cells ‡. | 2019 Dec 30 |
3 |
| 27 |
29355603 | Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease. | 2018 Apr |
2 |
| 28 |
29413957 | 2-Chlorohexadecanoic acid induces ER stress and mitochondrial dysfunction in brain microvascular endothelial cells. | 2018 May |
2 |
| 29 |
29581853 | The protective autophagy activated by GANT-61 in MYCN amplified neuroblastoma cells is mediated by PERK. | 2018 Mar 6 |
1 |
| 30 |
29708817 | Montelukast inhibits hypoxia inducible factor-1α translation in prostate cancer cells. | 2018 Aug 3 |
2 |
| 31 |
30293566 | PERK inhibition attenuates the abnormalities of the secretory pathway and the increased apoptotic rate induced by SIL1 knockdown in HeLa cells. | 2018 Oct |
1 |
| 32 |
27888615 | Unconjugated secondary bile acids activate the unfolded protein response and induce golgi fragmentation via a src-kinase-dependant mechanism. | 2017 Jan 3 |
1 |
| 33 |
28358434 | Effects of GSK2606414 on cell proliferation and endoplasmic reticulum stress‑associated gene expression in retinal pigment epithelial cells. | 2017 May |
2 |
| 34 |
28703114 | Inhibition of PERK-dependent pro-adaptive signaling pathway as a promising approach for cancer treatment. | 2017 Jun 30 |
3 |
| 35 |
28867746 | Modulation of Unfolded Protein Response by Methylmercury. | 2017 |
1 |
| 36 |
25663310 | Autophagy and protein kinase RNA-like endoplasmic reticulum kinase (PERK)/eukaryotic initiation factor 2 alpha kinase (eIF2α) pathway protect ovarian cancer cells from metformin-induced apoptosis. | 2016 Apr |
1 |
| 37 |
26902409 | Evodiamine from Evodia rutaecarpa induces apoptosis via activation of JNK and PERK in human ovarian cancer cells. | 2016 Jan 15 |
2 |
| 38 |
27226638 | Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses. | 2016 Jul 22 |
2 |
| 39 |
24900593 | Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development. | 2013 Oct 10 |
2 |
| 40 |
22827572 | Discovery of 7-methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a potent and selective first-in-class inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). | 2012 Aug 23 |
2 |