dabrafenib


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168 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 560
2 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 78
3 zinc fingers and homeoboxes 2 ZHX2_HUMAN ZHX2 Homo sapiens 22882 627 23
4 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 19
5 Braf transforming gene BRAF_MOUSE Braf Mus musculus 109880 159 14
6 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 10
7 mitogen-activated protein kinase kinase 1 MP2K1_HUMAN MAP2K1 Homo sapiens 5604 739 9
8 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 6
9 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 6
10 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 5
11 NRAS proto-oncogene, GTPase RASN_HUMAN NRAS Homo sapiens 4893 357 5
12 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 5
13 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 4
14 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 4
15 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 4
16 receptor interacting serine/threonine kinase 3 RIPK3_HUMAN RIPK3 Homo sapiens 11035 184 4
17 cytochrome P450 family 2 subfamily C member 8 CP2C8_HUMAN CYP2C8 Homo sapiens 1558 590 4
18 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 4
19 receptor-interacting serine-threonine kinase 3 RIPK3_MOUSE Ripk3 Mus musculus 56532 173 4
20 Raf-1 proto-oncogene, serine/threonine kinase RAF1_HUMAN RAF1 Homo sapiens 5894 636 4
21 nuclear receptor subfamily 1 group I member 2 NR1I2_HUMAN NR1I2 Homo sapiens 8856 820 3
22 UDP glucuronosyltransferase family 1 member A1 UD11_HUMAN UGT1A1 Homo sapiens 54658 747 3
23 mixed lineage kinase domain like pseudokinase MLKL_HUMAN MLKL Homo sapiens 197259 160 3
24 mitogen-activated protein kinase kinase 2 MP2K2_HUMAN MAP2K2 Homo sapiens 5605 75 3
25 B-Raf proto-oncogene, serine/threonine kinase - Braf Rattus norvegicus 114486 54 2
26 mitogen-activated protein kinase 3 MK03_MOUSE Mapk3 Mus musculus 26417 1527 2
27 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 2
28 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 2
29 cytotoxic T-lymphocyte associated protein 4 CTLA4_HUMAN CTLA4 Homo sapiens 1493 351 2
30 LIM domain kinase 1 LIMK1_HUMAN LIMK1 Homo sapiens 3984 131 2
31 cyclin dependent kinase 16 CDK16_HUMAN CDK16 Homo sapiens 5127 17 2
32 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 2
33 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 2
34 high mobility group box 1 HMGB1_HUMAN HMGB1 Homo sapiens 3146 785 2
35 phosphoglycolate phosphatase PGP_HUMAN PGP Homo sapiens 283871 1342 2
36 twist family bHLH transcription factor 1 TWST1_HUMAN TWIST1 Homo sapiens 7291 370 2
37 cytochrome P450 family 2 subfamily C member 9 CP2C9_HUMAN CYP2C9 Homo sapiens 1559 1244 2
38 eukaryotic translation initiation factor 2 alpha kinase 3 E2AK3_HUMAN EIF2AK3 Homo sapiens 9451 737 2
39 zinc fingers and homeoboxes 2 ZHX2_MOUSE Zhx2 Mus musculus 387609 161 2
40 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 2
41 telomerase reverse transcriptase TERT_HUMAN TERT Homo sapiens 7015 997 2
42 BH3 interacting domain death agonist BID_HUMAN BID Homo sapiens 637 1130 2
43 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 2
44 5'-nucleotidase ecto 5NTD_HUMAN NT5E Homo sapiens 4907 569 2
45 Rac family small GTPase 1 RAC1_HUMAN RAC1 Homo sapiens 5879 884 2
46 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 2
47 albumin ALBU_HUMAN ALB Homo sapiens 213 5631 2
48 albumin ALBU_MOUSE Alb Mus musculus 11657 717 2
49 CD22 molecule CD22_HUMAN CD22 Homo sapiens 933 182 1
50 KRAS proto-oncogene, GTPase RASK_RAT Kras Rattus norvegicus 24525 564 1