Protein Name cytochrome P450 family 2 subfamily C member 8
Organism Homo sapiens
Gene ID 1558
Gene Symbol


UniProt P10632 (CP2C8_HUMAN), B7Z1F5 (B7Z1F5_HUMAN)
Relationships Total Number of functionally related compound(s) : 590
Total Number of Articles : 694

cytochrome P450 family 2 subfamily C member 8

Gene Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

  • cytochrome P450 2C8
  • P450 form 1
  • cytochrome P450 IIC2
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