Protein Name cytochrome P450 family 2 subfamily C member 9
Organism Homo sapiens
Gene ID 1559
Gene Symbol


UniProt P11712 (CP2C9_HUMAN), S5RV20 (S5RV20_HUMAN)
Relationships Total Number of functionally related compound(s) : 1244
Total Number of Articles : 2604

cytochrome P450 family 2 subfamily C member 9

Gene Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]

  • cytochrome P450 2C9
  • cytochrome P-450 S-mephenytoin 4-hydroxylase
  • cytochrome P-450MP
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