dabrafenib

NRAS proto-oncogene, GTPase ; Homo sapiens







5 Article(s)
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1 33921947 A Phase 2 Clinical Trial of Trametinib and Low-Dose Dabrafenib in Patients with Advanced Pretreated NRASQ61R/K/L Mutant Melanoma (TraMel-WT). 2021 Apr 22 1
2 32388065 Molecular mechanisms of resistance to BRAF and MEK inhibitors in BRAFV600E non-small cell lung cancer. 2020 Jun 1
3 29112787 Dabrafenib inhibits the growth of BRAF-WT cancers through CDK16 and NEK9 inhibition. 2018 Jan 2
4 29631033 An Acquired NRAS Q61K Mutation in BRAF V600E-Mutant Lung Adenocarcinoma Resistant to Dabrafenib Plus Trametinib. 2018 Aug 1
5 22389471 Combinations of BRAF, MEK, and PI3K/mTOR inhibitors overcome acquired resistance to the BRAF inhibitor GSK2118436 dabrafenib, mediated by NRAS or MEK mutations. 2012 Apr 7