Protein Name high mobility group box 1
Organism Homo sapiens
Gene ID 3146
Gene Symbol


UniProt P09429 (HMGB1_HUMAN), A0A024RDR0 (A0A024RDR0_HUMAN)
Relationships Total Number of functionally related compound(s) : 785
Total Number of Articles : 1251

high mobility group box 1

Gene Summary

This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]

  • high mobility group protein B1
  • Amphoterin
  • Sulfoglucuronyl carbohydrate binding protein
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