dabrafenib

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







6 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34780725 Dabrafenib inhibits ABCG2 and cytochrome P450 isoenzymes; potential implications for combination anticancer therapy. 2022 Jan 1 3
2 33932130 Evaluation of the Effects of Repeat-Dose Dabrafenib on the Single-Dose Pharmacokinetics of Rosuvastatin (OATP1B1/1B3 Substrate) and Midazolam (CYP3A4 Substrate). 2021 Sep 1
3 30094711 Clinical Pharmacokinetics and Pharmacodynamics of Dabrafenib. 2019 Apr 3
4 29574693 Physiologically Based Pharmacokinetic Modeling to Identify Physiological and Molecular Characteristics Driving Variability in Drug Exposure. 2018 Dec 1
5 25449654 Assessment of the drug interaction potential and single- and repeat-dose pharmacokinetics of the BRAF inhibitor dabrafenib. 2015 Apr 1
6 24748562 The metabolic drug-drug interaction profile of Dabrafenib: in vitro investigations and quantitative extrapolation of the P450-mediated DDI risk. 2014 Jul 3