U 0126


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2042 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 993
2 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 805
3 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 774
4 mitogen-activated protein kinase kinase 1 MP2K1_HUMAN MAP2K1 Homo sapiens 5604 739 436
5 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 349
6 mitogen-activated protein kinase 1 MK01_MOUSE Mapk1 Mus musculus 26413 1992 329
7 Eph receptor B1 EPHB1_RAT Ephb1 Rattus norvegicus 24338 1417 253
8 mitogen-activated protein kinase 3 MK03_MOUSE Mapk3 Mus musculus 26417 1527 230
9 midkine MK_MOUSE Mdk Mus musculus 17242 501 167
10 mitogen activated protein kinase kinase 1 MP2K1_RAT Map2k1 Rattus norvegicus 170851 269 144
11 mitogen-activated protein kinase kinase 1 MP2K1_MOUSE Map2k1 Mus musculus 26395 224 107
12 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 93
13 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 79
14 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 73
15 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 71
16 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 67
17 epidermal growth factor EGF_HUMAN EGF Homo sapiens 1950 1636 57
18 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 49
19 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 46
20 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 44
21 interferon induced protein 44 IFI44_HUMAN IFI44 Homo sapiens 10561 347 42
22 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 42
23 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 37
24 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 35
25 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 33
26 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 33
27 mitogen-activated protein kinase 14 MK14_MOUSE Mapk14 Mus musculus 26416 2012 30
28 cyclin dependent kinase 20 CDK20_HUMAN CDK20 Homo sapiens 23552 299 29
29 mitogen-activated protein kinase kinase 2 MP2K2_HUMAN MAP2K2 Homo sapiens 5605 75 29
30 Jun proto-oncogene, AP-1 transcription factor subunit JUN_HUMAN JUN Homo sapiens 3725 1260 29
31 Fos proto-oncogene, AP-1 transcription factor subunit FOS_HUMAN FOS Homo sapiens 2353 1431 27
32 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 26
33 cadherin 1 CADH1_HUMAN CDH1 Homo sapiens 999 1360 26
34 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 25
35 mitogen activated protein kinase 14 Q56A33_RAT Mapk14 Rattus norvegicus 81649 1429 25
36 hepatocyte growth factor HGF_HUMAN HGF Homo sapiens 3082 1036 24
37 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 24
38 fibroblast growth factor 2 FGF2_HUMAN FGF2 Homo sapiens 2247 1502 24
39 EPH receptor B2 EPHB2_HUMAN EPHB2 Homo sapiens 2048 321 24
40 matrix metallopeptidase 1 MMP1_HUMAN MMP1 Homo sapiens 4312 1304 23
41 angiotensinogen ANGT_RAT Agt Rattus norvegicus 24179 2598 23
42 insulin like growth factor 1 IGF1_HUMAN IGF1 Homo sapiens 3479 1917 23
43 cAMP responsive element binding protein 1 CREB1_RAT Creb1 Rattus norvegicus 81646 811 23
44 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 23
45 cAMP responsive element binding protein 1 CREB1_HUMAN CREB1 Homo sapiens 1385 968 23
46 brain-derived neurotrophic factor BDNF_RAT Bdnf Rattus norvegicus 24225 1357 22
47 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 22
48 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 22
49 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 21
50 C-C motif chemokine ligand 2 CCL2_HUMAN CCL2 Homo sapiens 6347 1858 21