| 1 |
35485167 | MEK1/2 inhibitor inhibits neointima formation by activating miR-126-3p/ C-X-C motif chemokine ligand 12 (CXCL12)/C-X-C motif chemokine receptor 4 (CXCR4) axis. | 2022 Apr |
1 |
| 2 |
35504090 | Enhancement of vitamin C-induced myogenesis by inhibition of extracellular signal-regulated kinase (ERK) 1/2 pathway. | 2022 Jul 5 |
1 |
| 3 |
34099834 | Combination treatment with U0126 and rt-PA prevents adverse effects of the delayed rt-PA treatment after acute ischemic stroke. | 2021 Jun 7 |
1 |
| 4 |
31784089 | Combination of MEK1/2 inhibitor and LXR ligand synergistically inhibit atherosclerosis in LDLR deficient mice. | 2020 Feb 5 |
1 |
| 5 |
32330731 | Hypergastrinemia Expands Gastric ECL Cells Through CCK2R+ Progenitor Cells via ERK Activation. | 2020 |
1 |
| 6 |
30447218 | Scutellarin alleviates blood-retina-barrier oxidative stress injury initiated by activated microglia cells during the development of diabetic retinopathy. | 2019 Jan |
1 |
| 7 |
30946562 | 5-HT1B Receptor-Mediated Activation of ERK1/2 Requires Both Gαi/o and β-Arrestin Proteins. | 2019 Jul 17 |
1 |
| 8 |
31148200 | Immunomodulatory activity of Ganoderma lucidum immunomodulatory protein via PI3K/Akt and MAPK signaling pathways in RAW264.7 cells. | 2019 Dec |
1 |
| 9 |
31336670 | Regulation of Acetylcholine Quantal Release by Coupled Thrombin/BDNF Signaling in Mouse Motor Synapses. | 2019 Jul 22 |
1 |
| 10 |
31682623 | Retinoic acid-stimulated ERK1/2 pathway regulates meiotic initiation in cultured fetal germ cells. | 2019 |
1 |
| 11 |
31768875 | The antidepressant-like effect of guanosine is dependent on GSK-3β inhibition and activation of MAPK/ERK and Nrf2/heme oxygenase-1 signaling pathways. | 2019 Dec |
1 |
| 12 |
32009900 | Astrocytes and Microglia Are Resistant to NAD+-Mediated Cell Death Along the ARTC2/P2X7 Axis. | 2019 |
1 |
| 13 |
29397067 | Drp1 phosphorylation by MAPK1 causes mitochondrial dysfunction in cell culture model of Huntington's disease. | 2018 Feb 5 |
1 |
| 14 |
29436684 | Lactoferrin promotes murine C2C12 myoblast proliferation and differentiation and myotube hypertrophy. | 2018 Apr |
1 |
| 15 |
29518531 | Entrainment of the Circadian Clock in Neural Stem Cells by Epidermal Growth Factor is Closely Associated with ERK1/2-mediated Induction of Multiple Clock-related Genes. | 2018 May 21 |
1 |
| 16 |
29673908 | Mechanism underlying the contractile activity of UTP in the mammalian heart. | 2018 Jul 5 |
1 |
| 17 |
30316871 | Downregulation of heat shock factor 4 transcription activity via MAPKinase phosphorylation at Serine 299. | 2018 Dec |
1 |
| 18 |
26916448 | Airborne fine particulate matter causes murine bronchial hyperreactivity via MAPK pathway-mediated M3 muscarinic receptor upregulation. | 2017 Feb |
1 |
| 19 |
28034754 | LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway. | 2017 Jan 29 |
1 |
| 20 |
28697633 | Zinc L-carnosine suppresses inflammatory responses in lipopolysaccharide-induced RAW 264.7 murine macrophages cell line via activation of Nrf2/HO-1 signaling pathway. | 2017 Oct |
1 |
| 21 |
28822602 | Time-dependent role of prefrontal cortex and hippocampus on cognitive improvement by aripiprazole in olfactory bulbectomized mice. | 2017 Oct |
1 |
| 22 |
29299041 | Ascorbic acid promotes 3T3-L1 cells adipogenesis by attenuating ERK signaling to upregulate the collagen VI. | 2017 |
1 |
| 23 |
29358904 | Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes. | 2017 |
1 |
| 24 |
26862884 | Fluoride-induced c-Fos expression in MC3T3-E1 osteoblastic cells. | 2016 Feb |
1 |
| 25 |
27045084 | MEK1/2 inhibitors induce interleukin-5 expression in mouse macrophages and lymphocytes. | 2016 May 13 |
2 |
| 26 |
27629357 | Low frequency pulsed electromagnetic field promotes C2C12 myoblasts proliferation via activation of MAPK/ERK pathway. | 2016 Oct 7 |
1 |
| 27 |
24947959 | Inhibition of tumor growth by U0126 is associated with induction of interferon-γ production. | 2015 Feb 15 |
2 |
| 28 |
25562430 | Oncostatin M regulates SOCS3 mRNA stability via the MEK-ERK1/2-pathway independent of p38(MAPK)/MK2. | 2015 Mar |
1 |
| 29 |
26356837 | G Protein-Coupled Estrogen Receptor 1 Mediates Acute Estrogen-Induced Cardioprotection via MEK/ERK/GSK-3β Pathway after Ischemia/Reperfusion. | 2015 |
4 |
| 30 |
22751110 | Estrogen receptor beta growth-inhibitory effects are repressed through activation of MAPK and PI3K signalling in mammary epithelial and breast cancer cells. | 2013 May 9 |
1 |
| 31 |
22875335 | Monitoring therapy with MEK inhibitor U0126 in a novel Wilms tumor model in Wt1 knockout Igf2 transgenic mice using 18F-FDG PET with dual-contrast enhanced CT and MRI: early metabolic response without inhibition of tumor growth. | 2013 Apr |
1 |
| 32 |
23386286 | Rosuvastatin enhances the therapeutic efficacy of adipose-derived mesenchymal stem cells for myocardial infarction via PI3K/Akt and MEK/ERK pathways. | 2013 Mar |
1 |
| 33 |
23786209 | Identification of integrin α3 as a molecular marker of cells undergoing epithelial-mesenchymal transition and of cancer cells with aggressive phenotypes. | 2013 Sep |
1 |
| 34 |
21945831 | Liver fibrosis protects mice from acute hepatocellular injury. | 2012 Jan |
1 |
| 35 |
22326785 | Reduction of metastasis, cell invasion, and adhesion in mouse osteosarcoma by YM529/ONO-5920-induced blockade of the Ras/MEK/ERK and Ras/PI3K/Akt pathway. | 2012 Mar 15 |
1 |
| 36 |
22427990 | N-cadherin mediates neuronal cell survival through Bim down-regulation. | 2012 |
1 |
| 37 |
22570747 | Epigallocatechin-3-gallate Inhibits LPS-Induced NF-κB and MAPK Signaling Pathways in Bone Marrow-Derived Macrophages. | 2012 Apr |
1 |
| 38 |
22723831 | MEK1 inhibits cardiac PPARα activity by direct interaction and prevents its nuclear localization. | 2012 |
1 |
| 39 |
22859407 | α2C-Adrenoceptors modulate L-DOPA uptake in opossum kidney cells and in the mouse kidney. | 2012 Oct |
1 |
| 40 |
22912494 | The protease Omi cleaves the mitogen-activated protein kinase kinase MEK1 to inhibit microglial activation. | 2012 Aug 21 |
1 |
| 41 |
22956516 | cAMP-dependent regulation of ovulatory response genes is amplified by IGF1 due to synergistic effects on Akt phosphorylation and NF-κB transcription factors. | 2012 Nov |
1 |
| 42 |
21439396 | Doxycycline up-regulates the expression of IL-6 and GM-CSF via MAPK/ERK and NF-κB pathways in mouse thymic epithelial cells. | 2011 Sep |
1 |
| 43 |
21558393 | Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis. | 2011 Jul 1 |
1 |
| 44 |
21711332 | Ultraviolet B radiation and reactive oxygen species modulate interleukin-31 expression in T lymphocytes, monocytes and dendritic cells. | 2011 Nov |
1 |
| 45 |
19913294 | The effect of timing in the administration of hepatocyte growth factor to modulate BMP-2-induced osteoblast differentiation. | 2010 Feb |
1 |
| 46 |
20450880 | Suppression mechanisms of flavonoids on aryl hydrocarbon receptor-mediated signal transduction. | 2010 Sep 1 |
1 |
| 47 |
20469933 | Protein kinase C epsilon regulation of translocator protein (18 kDa) Tspo gene expression is mediated through a MAPK pathway targeting STAT3 and c-Jun transcription factors. | 2010 Jun 15 |
1 |
| 48 |
20470842 | AMPAR signaling mediating GABA(A)R delta subunit up-regulation in cultured mouse cerebellar granule cells. | 2010 Sep |
1 |
| 49 |
20557427 | p90 activation contributes to cerebral ischemic damage via phosphorylation of Na+/H+ exchanger isoform 1. | 2010 Sep 1 |
1 |
| 50 |
20589721 | Ganglioside GD1a suppression of NOS2 expression via ERK1 pathway in mouse osteosarcoma FBJ cells. | 2010 Aug 1 |
1 |