Protein Name cAMP responsive element binding protein 1
Organism Homo sapiens
Gene ID 1385
Gene Symbol


UniProt P16220 (CREB1_HUMAN), Q5U0J5 (Q5U0J5_HUMAN), Q53X93 (Q53X93_HUMAN), B7Z5C6 (B7Z5C6_HUMAN)
Relationships Total Number of functionally related compound(s) : 968
Total Number of Articles : 2588

cAMP responsive element binding protein 1

Gene Summary

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]

  • cyclic AMP-responsive element-binding protein 1
  • active transcription factor CREB
  • cAMP-response element-binding protein-1
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