Protein Name cAMP responsive element binding protein 1
Organism Rattus norvegicus
Gene ID 81646
Gene Symbol

Creb1

UniProt P15337 (CREB1_RAT)
Relationships Total Number of functionally related compound(s) : 811
Total Number of Articles : 1571
Description

cAMP responsive element binding protein 1

Gene Summary

Enables several functions, including Hsp70 protein binding activity; arrestin family protein binding activity; and histone acetyltransferase binding activity. Involved in several processes, including cellular response to growth factor stimulus; learning or memory; and regulation of gene expression. Located in several cellular components, including axon; chromatin; and mitochondrial matrix. Part of transcription regulator complex. Used to study transient cerebral ischemia. Biomarker of Huntington's disease; brain ischemia; and sciatic neuropathy. Orthologous to human CREB1 (cAMP responsive element binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cyclic AMP-responsive element-binding protein 1
  • CREB-1
  • Y protein
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Properties