Sunitinib


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779 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 245
2 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 166
3 KIT proto-oncogene, receptor tyrosine kinase KIT_HUMAN KIT Homo sapiens 3815 679 146
4 platelet derived growth factor receptor beta PGFRB_HUMAN PDGFRB Homo sapiens 5159 417 77
5 fms related receptor tyrosine kinase 3 FLT3_HUMAN FLT3 Homo sapiens 2322 569 67
6 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 52
7 platelet derived growth factor receptor alpha PGFRA_HUMAN PDGFRA Homo sapiens 5156 229 48
8 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 42
9 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 38
10 fms related receptor tyrosine kinase 1 VGFR1_HUMAN FLT1 Homo sapiens 2321 547 28
11 vascular endothelial growth factor A VEGFA_MOUSE Vegfa Mus musculus 22339 1647 28
12 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 27
13 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 21
14 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 21
15 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 20
16 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 19
17 kinase insert domain protein receptor VGFR2_MOUSE Kdr Mus musculus 16542 475 19
18 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 17
19 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 16
20 platelet derived growth factor receptor, beta polypeptide PGFRB_MOUSE Pdgfrb Mus musculus 18596 179 16
21 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 14
22 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 13
23 phosphatase and tensin homolog PTEN_HUMAN PTEN Homo sapiens 5728 1316 13
24 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 13
25 T cell receptor alpha constant - TRAC Homo sapiens 28755 80 12
26 vascular endothelial growth factor A VEGFA_RAT Vegfa Rattus norvegicus 83785 1424 12
27 endothelial PAS domain protein 1 EPAS1_HUMAN EPAS1 Homo sapiens 2034 257 12
28 interferon alpha 1 IFNA1_HUMAN IFNA1 Homo sapiens 3439 1490 12
29 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 12
30 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 11
31 fms related receptor tyrosine kinase 4 VGFR3_HUMAN FLT4 Homo sapiens 2324 142 11
32 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 11
33 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 11
34 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 11
35 AXL receptor tyrosine kinase UFO_HUMAN AXL Homo sapiens 558 302 10
36 colony stimulating factor 1 receptor CSF1R_HUMAN CSF1R Homo sapiens 1436 231 10
37 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 10
38 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_MOUSE Abcg2 Mus musculus 26357 461 10
39 KIT proto-oncogene receptor tyrosine kinase KIT_MOUSE Kit Mus musculus 16590 294 9
40 signal transducer and activator of transcription 3 STAT3_MOUSE Stat3 Mus musculus 20848 1288 9
41 TXK tyrosine kinase TXK_HUMAN TXK Homo sapiens 7294 195 8
42 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 8
43 von Hippel-Lindau tumor suppressor VHL_HUMAN VHL Homo sapiens 7428 215 8
44 angiopoietin 2 ANGP2_HUMAN ANGPT2 Homo sapiens 285 254 7
45 C-reactive protein CRP_HUMAN CRP Homo sapiens 1401 2285 7
46 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 7
47 kinase insert domain receptor VGFR2_RAT Kdr Rattus norvegicus 25589 312 7
48 interleukin 2 IL2_HUMAN IL2 Homo sapiens 3558 2456 7
49 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 7
50 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 6