Sunitinib

tumor protein p53 ; Homo sapiens







11 Article(s)
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1 34475048 P53 Is Involved in Sunitinib Resistance and Poor Progression-free Survival After Sunitinib Treatment of Renal Cell Carcinoma. 2021 Sep 9
2 31268155 Prognostic significance of VHL, HIF1A, HIF2A, VEGFA and p53 expression in patients with clear‑cell renal cell carcinoma treated with sunitinib as first‑line treatment. 2019 Aug 2
3 29435010 Chloroquine potentiates the anticancer effect of sunitinib on renal cell carcinoma by inhibiting autophagy and inducing apoptosis. 2018 Mar 1
4 30205729 HMGB1 represses the anti-cancer activity of sunitinib by governing TP53 autophagic degradation via its nucleus-to-cytoplasm transport. 2018 9
5 28870911 Sunitinib Inhibits Breast Cancer Cell Proliferation by Inducing Apoptosis, Cell-cycle Arrest and DNA Repair While Inhibiting NF-κB Signaling Pathways. 2017 Sep 2
6 27288242 The tyrosine kinase inhibitor, sunitinib malate, induces cognitive impairment in vivo via dysregulating VEGFR signaling, apoptotic and autophagic machineries. 2016 Sep 1
7 27485825 Synergy between von Hippel-Lindau and P53 contributes to chemosensitivity of clear cell renal cell carcinoma. 2016 Sep 1
8 23497256 Effects of HDM2 antagonism on sunitinib resistance, p53 activation, SDF-1 induction, and tumor infiltration by CD11b+/Gr-1+ myeloid derived suppressor cells. 2013 Mar 5 1
9 23578198 Sunitinib induces cellular senescence via p53/Dec1 activation in renal cell carcinoma cells. 2013 Aug 3
10 22314934 Antitumor effect of vascular endothelial growth factor inhibitor sunitinib in preclinical models of hepatocellular carcinoma. 2012 May 2
11 22662219 p53 modulation as a therapeutic strategy in gastrointestinal stromal tumors. 2012 1