CPRiL

Kdr

kinase insert domain receptor

Enables growth factor binding activity and vascular endothelial growth factor receptor activity. Involved in several processes, including positive regulation of endothelial cell proliferation; positive regulation of intracellular signal transduction; and positive regulation of long-term neuronal synaptic plasticity. Located in neuronal cell body. Used to study adhesions of uterus; brain ischemia; cystitis; and myocardial infarction. Biomarker of several diseases, including artery disease (multiple); impotence; ovarian hyperstimulation syndrome; prostate disease (multiple); and retinopathy of prematurity. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); breast angiosarcoma; gastrointestinal system cancer (multiple); macular degeneration (multiple); and pancreatic cancer (multiple). Orthologous to human KDR (kinase insert domain receptor). [provided by Alliance of Genome Resources, Jul 2025]

• vascular endothelial growth factor receptor 2
• FLK-1
• FLK1 kinase insert domain receptor (VEGF receptor 2)
FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2)
fetal liver kinase 1
kinase insert domain protein receptor
protein-tyrosine kinase receptor flk-1
Vegfr-2