Protein Name | ATP binding cassette subfamily G member 2 (Junior blood group) |
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Organism | Mus musculus |
Gene ID | 26357 |
Gene Symbol | Abcg2 |
UniProt | Q7TMS5 (ABCG2_MOUSE), A0A0R4J0B6 (A0A0R4J0B6_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
461
Total Number of Articles : 464 |
Description |
ATP binding cassette subfamily G member 2 (Junior blood group) |
Gene Summary |
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, the human protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. This protein likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. [provided by RefSeq, Jul 2008] |
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