pyrazolanthrone


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1194 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 1388
2 mitogen-activated protein kinase 8 MK08_MOUSE Mapk8 Mus musculus 26419 1537 410
3 mitogen-activated protein kinase 8 MK08_RAT Mapk8 Rattus norvegicus 116554 1068 341
4 Jun proto-oncogene, AP-1 transcription factor subunit JUN_HUMAN JUN Homo sapiens 3725 1260 143
5 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 91
6 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 87
7 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 67
8 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 58
9 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 58
10 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 41
11 jun proto-oncogene JUN_MOUSE Jun Mus musculus 16476 900 40
12 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 40
13 matrix metallopeptidase 9 MMP9_HUMAN MMP9 Homo sapiens 4318 2470 36
14 BCL2 associated X, apoptosis regulator BAX_HUMAN BAX Homo sapiens 581 3031 34
15 mitogen activated protein kinase 14 Q56A33_RAT Mapk14 Rattus norvegicus 81649 1429 31
16 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 30
17 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 28
18 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 28
19 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 28
20 mitogen-activated protein kinase 14 MK14_MOUSE Mapk14 Mus musculus 26416 2012 27
21 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 27
22 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 25
23 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 25
24 caspase 3 CASP3_RAT Casp3 Rattus norvegicus 25402 2178 24
25 transforming growth factor beta 1 TGFB1_HUMAN TGFB1 Homo sapiens 7040 2953 24
26 mitogen-activated protein kinase 9 MK09_HUMAN MAPK9 Homo sapiens 5601 287 22
27 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 22
28 mitogen-activated protein kinase 1 MK01_MOUSE Mapk1 Mus musculus 26413 1992 21
29 angiotensinogen ANGT_RAT Agt Rattus norvegicus 24179 2598 21
30 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 21
31 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 20
32 C-C motif chemokine ligand 2 CCL2_HUMAN CCL2 Homo sapiens 6347 1858 19
33 cytochrome c, somatic CYC_HUMAN CYCS Homo sapiens 54205 3740 19
34 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 17
35 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 17
36 interleukin 1 beta Q5BKB0_RAT Il1b Rattus norvegicus 24494 2252 16
37 BCL2 associated X, apoptosis regulator G3V8T9_RAT Bax Rattus norvegicus 24887 1472 15
38 nitric oxide synthase 2, inducible NOS2_MOUSE Nos2 Mus musculus 18126 2585 15
39 BCL2, apoptosis regulator BCL2_RAT Bcl2 Rattus norvegicus 24224 1676 15
40 heme oxygenase 1 HMOX1_HUMAN HMOX1 Homo sapiens 3162 1764 14
41 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 14
42 insulin INS_HUMAN INS Homo sapiens 3630 7950 14
43 matrix metallopeptidase 1 MMP1_HUMAN MMP1 Homo sapiens 4312 1304 14
44 mitogen-activated protein kinase 8 A0A480EHQ8_PIG MAPK8 Sus scrofa 396610 48 14
45 Eph receptor B1 EPHB1_RAT Ephb1 Rattus norvegicus 24338 1417 14
46 mitogen-activated protein kinase kinase 1 MP2K1_HUMAN MAP2K1 Homo sapiens 5604 739 14
47 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 13
48 intercellular adhesion molecule 1 ICAM1_HUMAN ICAM1 Homo sapiens 3383 1840 13
49 angiotensinogen ANGT_HUMAN AGT Homo sapiens 183 2109 13
50 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 NFKB1_MOUSE Nfkb1 Mus musculus 18033 3161 12