pyrazolanthrone

caspase 3 ; Homo sapiens







58 Article(s)
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1 34472704 The molecular mechanism of GADD153 in apoptosis of keloid fibroblasts exposed to botulinum toxin type A. 2021 Oct 1
2 32373311 JNK Signaling Pathway Suppresses LPS-Mediated Apoptosis of HK-2 Cells by Upregulating NGAL. 2020 2
3 32717251 Involvement of endoplasmic reticulum stress response and IRE1-mediated ASK1/JNK/Mcl-1 pathways in silver nanoparticle-induced apoptosis of human retinal pigment epithelial cells. 2020 Sep 1
4 32922532 Propranolol induced apoptosis and autophagy via the ROS/JNK signaling pathway in Human Ovarian Cancer. 2020 1
5 33281919 Shenshuaikang Enema, a Chinese Herbal Remedy, Inhibited Hypoxia and Reoxygenation-Induced Apoptosis in Renal Tubular Epithelial Cells by Inhibiting Oxidative Damage-Dependent JNK/Caspase-3 Signaling Pathways Using Network Pharmacology. 2020 2
6 30829205 MiR-145 inhibited lipopolysaccharide-induced apoptosis of gastric mucosal via up-regulating JNK-mediated cytoprotective autophagy. 2019 Jan 1
7 31357761 [Effect and mechanism of liraglutide on the apoptosis of human hepatocellular carcinoma HepG2 cells induced with palmitic acid]. 2019 Jun 20 1
8 31362241 ANXA3 Silencing Ameliorates Intracranial Aneurysm via Inhibition of the JNK Signaling Pathway. 2019 Sep 6 1
9 29383484 2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human gastric cancer cells through downregulating JNK-mediated cytoprotective autophagy. 2018 Mar 1
10 29434974 Dihydroartemisinin treatment of multiple myeloma cells causes activation of c-Jun leading to cell apoptosis. 2018 Feb 1
11 29552858 [Effect of ophiopogonin D in resisting vascular endothelial cell apoptosis induced by AngⅡthrough up-regulating CYP2J2/EETs]. 2018 Jan 1
12 28178378 Melatonin promotes sorafenib-induced apoptosis through synergistic activation of JNK/c-jun pathway in human hepatocellular carcinoma. 2017 Apr 1
13 28720813 A new Prenylated Flavonoid induces G0/G1 arrest and apoptosis through p38/JNK MAPK pathways in Human Hepatocellular Carcinoma cells. 2017 Jul 18 1
14 28756921 Experimental study on the apoptosis of cervical cancer Hela cells induced by juglone through c-Jun N-terminal kinase/c-Jun pathway. 2017 Jun 2
15 26985944 Paclitaxel induces apoptosis in leukemia cells through a JNK activation-dependent pathway. 2016 Mar 11 1
16 27924151 Effect of SP600125 on the mitotic spindle in HeLa Cells, leading to mitotic arrest, endoreduplication and apoptosis. 2016 1
17 23836369 Activation of MAPK pathways and downstream transcription factors in 2-aminobiphenyl-induced apoptosis. 2015 Feb 1
18 25178491 2-(Pro-1-ynyl)-5-(5,6-dihydroxypenta-1,3-diynyl) thiophene induces apoptosis through reactive oxygen species-mediated JNK activation in human colon cancer SW620 cells. 2015 Feb 1
19 25607831 CDK5RAP1 deficiency induces cell cycle arrest and apoptosis in human breast cancer cell line by the ROS/JNK signaling pathway. 2015 Mar 1
20 25839175 The protective role of (-)-epigallocatechin-3-gallate in thrombin-induced neuronal cell apoptosis and JNK-MAPK activation. 2015 May 6 1
21 26287183 15,16-Dihydrotanshinone I from the Functional Food Salvia miltiorrhiza Exhibits Anticancer Activity in Human HL-60 Leukemia Cells: in Vitro and in Vivo Studies. 2015 Aug 17 1
22 26335364 Lactoferrin attenuates fatty acid-induced lipotoxicity via Akt signaling in hepatocarcinoma cells. 2015 Dec 1
23 24461294 Inhibition of protein kinase C α/βII and activation of c-Jun NH2-terminal kinase mediate glycyrrhetinic acid induced apoptosis in non-small cell lung cancer NCI-H460 cells. 2014 Feb 15 1
24 24624962 ZnO nanoparticle-induced oxidative stress triggers apoptosis by activating JNK signaling pathway in cultured primary astrocytes. 2014 Mar 13 1
25 22733377 Antitumor effects of novel compound, guttiferone K, on colon cancer by p21Waf1/Cip1-mediated G(0) /G(1) cell cycle arrest and apoptosis. 2013 Feb 1 1
26 22990021 Perfluorooctane sulfonate-induced apoptosis of cerebellar granule cells is mediated by ERK 1/2 pathway. 2013 Feb 1
27 23850994 Akebia saponin PA induces autophagic and apoptotic cell death in AGS human gastric cancer cells. 2013 Sep 1
28 22610511 Human adipose tissue-derived stem cells protect impaired cardiomyocytes from hypoxia/reoxygenation injury through hypoxia-induced paracrine mechanism. 2012 Aug 1
29 23007278 Snake venom toxin from Vipera lebetina turanica sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins. 2012 Dec 1
30 23326144 c-Jun N-terminal kinase is required for thermotherapy-induced apoptosis in human gastric cancer cells. 2012 Dec 28 1
31 21082355 Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism. 2011 Feb 1
32 21569548 Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells. 2011 May 14 1
33 21856377 Activation of caspase-3 and c-Jun NH2-terminal kinase signaling pathways involving heroin-induced neuronal apoptosis. 2011 Sep 20 1
34 19846041 Apoptosis induction in BEFV-infected Vero and MDBK cells through Src-dependent JNK activation regulates caspase-3 and mitochondria pathways. 2010 Mar-Apr 1
35 20573157 High glucose induces apoptosis in AC16 human cardiomyocytes via macrophage migration inhibitory factor and c-Jun N-terminal kinase. 2010 Oct 1
36 20632440 8-Bromo-7-methoxychrysin-induced apoptosis of hepatocellular carcinoma cells involves ROS and JNK. 2010 Jul 21 1
37 20709060 The JNK inhibitor SP600125 enhances dihydroartemisinin-induced apoptosis by accelerating Bax translocation into mitochondria in human lung adenocarcinoma cells. 2010 Sep 24 1
38 19454725 Lipopolysaccharide-induced apoptosis in transformed bovine brain endothelial cells and human dermal microvessel endothelial cells: the role of JNK. 2009 Jun 1 1
39 19478553 JNK inhibitor SP600125 promotes the formation of polymerized tubulin, leading to G2/M phase arrest, endoreduplication, and delayed apoptosis. 2009 Sep 30 1
40 19486916 Role of oxidative stress and JNK pathway in apoptotic death induced by potassium deprivation and staurosporine in cerebellar granule neurons. 2009 Dec 1
41 17900936 Human TAO kinase 1 induces apoptosis in SH-SY5Y cells. 2008 Jan 1
42 18325654 Involvement of oxidative stress-activated JNK signaling in the methamphetamine-induced cell death of human SH-SY5Y cells. 2008 Apr 18 1
43 18343029 Bcl-2 overexpression attenuates SP600125-induced apoptosis in human leukemia U937 cells. 2008 Jun 18 2
44 18594007 Moscatilin induces apoptosis in human colorectal cancer cells: a crucial role of c-Jun NH2-terminal protein kinase activation caused by tubulin depolymerization and DNA damage. 2008 Jul 1 1
45 18636161 The association of deamidation of Bcl-xL and translocation of Bax to the mitochondria through activation of JNK in the induction of apoptosis by treatment with GSH-conjugated DXR. 2008 Aug 1
46 18703135 Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5. 2008 Oct 1 1
47 16909121 Overcoming the radioresistance of prostate cancer cells with a novel Bcl-2 inhibitor. 2007 Feb 1 1
48 17131386 Apoptotic signaling in methylglyoxal-treated human osteoblasts involves oxidative stress, c-Jun N-terminal kinase, caspase-3, and p21-activated kinase 2. 2007 Mar 1 1
49 17368702 Involvement of c-jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by cardiotoxin III (Naja naja atra) in K562 leukemia cells. 2007 Jun 1 1
50 17397922 Involvement of c-Jun N-terminal kinase in G2/M arrest and FasL-mediated apoptosis induced by a novel indoloquinoline derivative, IQDMA, in K562 cells. 2007 Oct 1