Vemurafenib


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415 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 1008
2 zinc fingers and homeoboxes 2 ZHX2_HUMAN ZHX2 Homo sapiens 22882 627 66
3 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 65
4 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 56
5 Braf transforming gene BRAF_MOUSE Braf Mus musculus 109880 159 41
6 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 31
7 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 27
8 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 25
9 NRAS proto-oncogene, GTPase RASN_HUMAN NRAS Homo sapiens 4893 357 13
10 mitogen-activated protein kinase kinase 1 MP2K1_HUMAN MAP2K1 Homo sapiens 5604 739 12
11 Raf-1 proto-oncogene, serine/threonine kinase RAF1_HUMAN RAF1 Homo sapiens 5894 636 11
12 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 10
13 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 8
14 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 8
15 eukaryotic translation initiation factor 2 alpha kinase 3 E2AK3_HUMAN EIF2AK3 Homo sapiens 9451 737 8
16 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 7
17 melanocyte inducing transcription factor MITF_HUMAN MITF Homo sapiens 4286 229 7
18 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 6
19 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 6
20 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 6
21 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 5
22 erb-b2 receptor tyrosine kinase 3 ERBB3_HUMAN ERBB3 Homo sapiens 2065 299 5
23 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 5
24 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 5
25 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 4
26 MET proto-oncogene, receptor tyrosine kinase MET_HUMAN MET Homo sapiens 4233 791 4
27 heat shock protein 90 alpha family class A member 1 HS90A_HUMAN HSP90AA1 Homo sapiens 3320 1552 4
28 Yes1 associated transcriptional regulator YAP1_HUMAN YAP1 Homo sapiens 10413 666 4
29 EPH receptor B2 EPHB2_HUMAN EPHB2 Homo sapiens 2048 321 4
30 microRNA 211 - MIR211 Homo sapiens 406993 34 4
31 matrix metallopeptidase 2 MMP2_HUMAN MMP2 Homo sapiens 4313 2342 4
32 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 4
33 v-raf-leukemia viral oncogene 1 RAF1_MOUSE Raf1 Mus musculus 110157 224 4
34 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 4
35 cyclin dependent kinase 4 CDK4_HUMAN CDK4 Homo sapiens 1019 868 4
36 CD4 molecule CD4_HUMAN CD4 Homo sapiens 920 2744 4
37 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 3
38 TNF receptor superfamily member 10b TR10B_HUMAN TNFRSF10B Homo sapiens 8795 608 3
39 cytochrome P450 family 1 subfamily A member 2 CP1A2_HUMAN CYP1A2 Homo sapiens 1544 1532 3
40 hepatocyte growth factor HGF_HUMAN HGF Homo sapiens 3082 1036 3
41 cyclin dependent kinase inhibitor 2A ARF_HUMAN CDKN2A Homo sapiens 1029 859 3
42 mitogen-activated protein kinase 1 MK01_MOUSE Mapk1 Mus musculus 26413 1992 3
43 hypoxia inducible factor 1 subunit alpha HIF1A_HUMAN HIF1A Homo sapiens 3091 2152 3
44 B-Raf proto-oncogene, serine/threonine kinase - BRAF Canis lupus familiaris 475526 15 3
45 cellular communication network factor 2 CCN2_HUMAN CCN2 Homo sapiens 1490 467 3
46 killer cell lectin like receptor K1 NKG2D_HUMAN KLRK1 Homo sapiens 22914 247 3
47 platelet derived growth factor receptor beta PGFRB_HUMAN PDGFRB Homo sapiens 5159 417 3
48 nucleophosmin 1 NPM_HUMAN NPM1 Homo sapiens 4869 371 3
49 activating transcription factor 4 ATF4_HUMAN ATF4 Homo sapiens 468 451 3
50 B-Raf proto-oncogene, serine/threonine kinase B3DFX5_DANRE braf Danio rerio 403065 5 3