Vemurafenib

NRAS proto-oncogene, GTPase ; Homo sapiens







13 Article(s)
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1 27790745 N-Ras mutation in vemurafenib-associated expanding melanocytic nevus. 2017 May 1
2 26460303 Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer. 2015 Dec 1 1
3 26608120 Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms. 2015 Dec 2
4 24422853 Inhibition of mutant BRAF splice variant signaling by next-generation, selective RAF inhibitors. 2014 May 1
5 24589925 Efficacy of intermittent combined RAF and MEK inhibition in a patient with concurrent BRAF- and NRAS-mutant malignancies. 2014 May 1
6 25063807 Mitogen-activated protein kinase (MAPK) hyperactivation and enhanced NRAS expression drive acquired vemurafenib resistance in V600E BRAF melanoma cells. 2014 Oct 3 5
7 23490205 Selective RAF inhibitor impairs ERK1/2 phosphorylation and growth in mutant NRAS, vemurafenib-resistant melanoma cells. 2013 Jul 2
8 23569304 Pharmacodynamic effects and mechanisms of resistance to vemurafenib in patients with metastatic melanoma. 2013 May 10 1
9 22256804 RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors. 2012 Jan 19 1
10 22395615 Melanoma whole-exome sequencing identifies (V600E)B-RAF amplification-mediated acquired B-RAF inhibitor resistance. 2012 Mar 6 1
11 28809522 Vemurafenib Therapy and BRAF and NRAS Genotype 2012 2
12 22194965 Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway. 2011 2
13 21107323 Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. 2010 Dec 16 2