Nicotine


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2377 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 cholinergic receptor nicotinic alpha 4 subunit ACHA4_HUMAN CHRNA4 Homo sapiens 1137 760 397
2 cholinergic receptor, nicotinic, alpha polypeptide 7 ACHA7_MOUSE Chrna7 Mus musculus 11441 464 326
3 cytochrome P450 family 2 subfamily A member 6 CP2A6_HUMAN CYP2A6 Homo sapiens 1548 512 240
4 cholinergic receptor nicotinic beta 1 subunit ACHB_RAT Chrnb1 Rattus norvegicus 24261 301 162
5 cholinergic receptor nicotinic alpha 2 subunit ACHA2_RAT Chrna2 Rattus norvegicus 170945 364 112
6 hemoglobin, beta adult minor chain HBB2_MOUSE Hbb-b2 Mus musculus 15130 337 102
7 cholinergic receptor nicotinic alpha 5 subunit ACHA5_HUMAN CHRNA5 Homo sapiens 1138 21 91
8 Fos proto-oncogene, AP-1 transcription factor subunit FOS_RAT Fos Rattus norvegicus 314322 1662 81
9 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 63
10 carbonic anhydrase 1 CAH1_RAT Car1 Rattus norvegicus 310218 1725 59
11 potassium calcium-activated channel subfamily M regulatory beta subunit 2 KCMB2_HUMAN KCNMB2 Homo sapiens 10242 1498 49
12 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 46
13 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 45
14 cholinergic receptor nicotinic alpha 3 subunit ACHA3_HUMAN CHRNA3 Homo sapiens 1136 16 43
15 tumor necrosis factor TNFA_MOUSE Tnf Mus musculus 21926 5931 41
16 dopamine receptor D2 DRD2_HUMAN DRD2 Homo sapiens 1813 660 39
17 brain-derived neurotrophic factor BDNF_RAT Bdnf Rattus norvegicus 24225 1357 38
18 proopiomelanocortin COLI_HUMAN POMC Homo sapiens 5443 2059 37
19 tumor necrosis factor TNFA_RAT Tnf Rattus norvegicus 24835 3922 35
20 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 34
21 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 34
22 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 34
23 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 33
24 arginine vasopressin NEU2_HUMAN AVP Homo sapiens 551 1345 33
25 brain derived neurotrophic factor BDNF_HUMAN BDNF Homo sapiens 627 1289 33
26 thymoma viral proto-oncogene 1 AKT1_MOUSE Akt1 Mus musculus 11651 3034 32
27 tyrosine hydroxylase TY3H_RAT Th Rattus norvegicus 25085 552 32
28 cannabinoid receptor 1 CNR1_RAT Cnr1 Rattus norvegicus 25248 570 31
29 immunoglobulin binding protein 1 IGBP1_HUMAN IGBP1 Homo sapiens 3476 258 31
30 arginine vasopressin NEU2_RAT Avp Rattus norvegicus 24221 1815 30
31 interleukin 6 IL6_MOUSE Il6 Mus musculus 16193 3985 29
32 cholinergic receptor nicotinic beta 4 subunit ACHB4_HUMAN CHRNB4 Homo sapiens 1143 9 28
33 immunoglobulin (CD79A) binding protein 1 IGBP1_MOUSE Igbp1 Mus musculus 18518 56 28
34 solute carrier family 6 member 3 SC6A3_HUMAN SLC6A3 Homo sapiens 6531 1098 26
35 opioid receptor mu 1 OPRM_HUMAN OPRM1 Homo sapiens 4988 700 26
36 cAMP responsive element binding protein 1 CREB1_RAT Creb1 Rattus norvegicus 81646 811 26
37 mitogen activated protein kinase 3 MK03_RAT Mapk3 Rattus norvegicus 50689 1665 25
38 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 25
39 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 25
40 interleukin 1 beta IL1B_HUMAN IL1B Homo sapiens 3553 3575 25
41 carbonic anhydrase 1 CAH1_MOUSE Car1 Mus musculus 12346 646 24
42 corticotropin releasing hormone CRF_RAT Crh Rattus norvegicus 81648 573 24
43 insulin INS_HUMAN INS Homo sapiens 3630 7950 23
44 catalase CATA_RAT Cat Rattus norvegicus 24248 1803 23
45 fibronectin 1 FINC_HUMAN FN1 Homo sapiens 2335 2017 22
46 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 22
47 cytochrome P450 family 2 subfamily B member 6 CP2B6_HUMAN CYP2B6 Homo sapiens 1555 1488 21
48 FBJ osteosarcoma oncogene FOS_MOUSE Fos Mus musculus 14281 1086 21
49 Fos proto-oncogene, AP-1 transcription factor subunit FOS_HUMAN FOS Homo sapiens 2353 1431 21
50 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 21