Nicotine

mitogen-activated protein kinase 1 ; Homo sapiens







45 Article(s)
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1 34890707 Nicotine stimulates IL-8 expression via ROS/NF-κB and ROS/MAPK/AP-1 axis in human gastric cancer cells. 2022 Jan 30 1
2 33276105 Choline and nicotine increase glioblastoma cell proliferation by binding and activating α7- and α9- containing nicotinic receptors. 2021 Jan 1
3 33355840 Changes in Mucin Production in Human Airway Epithelial Cells After Exposure to Electronic Cigarette Vapor With or Without Nicotine. 2021 Aug 1
4 34230140 Effects of Epstein-Barr Virus Infection on the Response of Human Breast Cancer Cells to Nicotine. 2021 Jul 1
5 32024069 Nicotine Induces IL-8 Secretion from Pancreatic Cancer Stroma and Worsens Cancer-Induced Cachexia. 2020 Feb 1 2
6 32649943 Nicotine inhibits MAPK signaling and spheroid invasion in ovarian cancer cells. 2020 Sep 1 3
7 30912145 Activation of α7-nAChRs protects SH-SY5Y cells from 1-methyl-4-phenylpyridinium-induced apoptotic cell death via ERK/p53 signaling pathway. 2019 Aug 3
8 29338098 Increase in motility and invasiveness of MCF7 cancer cells induced by nicotine is abolished by melatonin through inhibition of ERK phosphorylation. 2018 May 4
9 29039603 Blockade of α7 nicotinic acetylcholine receptors inhibit nicotine-induced tumor growth and vimentin expression in non-small cell lung cancer through MEK/ERK signaling way. 2017 Dec 2
10 26530054 Nicotine enhances invasion and metastasis of human colorectal cancer cells through the nicotinic acetylcholine receptor downstream p38 MAPK signaling pathway. 2016 Jan 4
11 27028622 Nicotine-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells. 2016 3
12 27907022 Nicotine Induces Podocyte Apoptosis through Increasing Oxidative Stress. 2016 2
13 25393899 Role of resistin in the inflammatory response induced by nicotine plus lipopolysaccharide in human periodontal ligament cells in vitro. 2015 Oct 1
14 25565665 HIF-2 Inhibition Supresses Inflammatory Responses and Osteoclastic Differentiation in Human Periodontal Ligament Cells. 2015 Jul 2
15 25815723 Low dose nicotine attenuates Aβ neurotoxicity through activation early growth response gene 1 pathway. 2015 1
16 26150803 Intra-ventral tegmental area HIV-1 Tat1-86 attenuates nicotine-mediated locomotor sensitization and alters mesocorticolimbic ERK and CREB signaling in rats. 2015 1
17 24201001 Exposure to ethanol and nicotine induces stress responses in human placental BeWo cells. 2014 Jan 13 2
18 24399025 Nicotine promotes cell proliferation and induces resistance to cisplatin by α7 nicotinic acetylcholine receptor‑mediated activation in Raw264.7 and El4 cells. 2014 Mar 1
19 24481039 Nicotine exerts neuroprotective effects against β-amyloid-induced neurotoxicity in SH-SY5Y cells through the Erk1/2-p38-JNK-dependent signaling pathway. 2014 Apr 4
20 22614999 Nicotine enhances proliferation, migration, and radioresistance of human malignant glioma cells through EGFR activation. 2013 Apr 2
21 23192567 Sodium hydrogen sulfide inhibits nicotine and lipopolysaccharide-induced osteoclastic differentiation and reversed osteoblastic differentiation in human periodontal ligament cells. 2013 May 1
22 23199342 Effects of sirtuin 1 activation on nicotine and lipopolysaccharide-induced cytotoxicity and inflammatory cytokine production in human gingival fibroblasts. 2013 Aug 1
23 23543412 Nicotine-induced structural plasticity in mesencephalic dopaminergic neurons is mediated by dopamine D3 receptors and Akt-mTORC1 signaling. 2013 Jun 2
24 24095863 Nicotine increases survival in human colon cancer cells treated with chemotherapeutic drugs. 2013 Dec 2
25 21070506 ERK1/2 protein and mRNA levels in human blood are linked to smoking behavior. 2012 Nov 1
26 22188668 Pancreatic cancer cells and normal pancreatic duct epithelial cells express an autocrine catecholamine loop that is activated by nicotinic acetylcholine receptors α3, α5, and α7. 2012 Feb 1
27 22791813 Effects of chronic nicotine on the autocrine regulation of pancreatic cancer cells and pancreatic duct epithelial cells by stimulatory and inhibitory neurotransmitters. 2012 Sep 1
28 22952803 Nicotine promotes proliferation of human nasopharyngeal carcinoma cells by regulating α7AChR, ERK, HIF-1α and VEGF/PEDF signaling. 2012 6
29 23149874 Nicotine induces the expression of C-reactive protein via MAPK-dependent signal pathway in U937 macrophages. 2012 Nov 1
30 21262190 Estradiol pretreatment attenuated nicotine-induced endothelial cell apoptosis via estradiol functional membrane receptor. 2011 Jun 2
31 20050989 Beneficial effects of melatonin on nicotine-induced vasculopathy. 2010 Mar 1
32 19804648 NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic cultures. 2009 Oct 5 4
33 18041576 Drug-induced alterations in the extracellular signal-regulated kinase (ERK) signalling pathway: implications for reinforcement and reinstatement. 2008 Feb 2
34 18448488 Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells. 2008 Aug 1
35 18805435 Nicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induce cyclooxygenase-2 activity in human gastric cancer cells: Involvement of nicotinic acetylcholine receptor (nAChR) and beta-adrenergic receptor signaling pathways. 2008 Dec 1 1
36 17003101 Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. 2007 Mar 1
37 17600315 Nicotine stimulates human lung cancer cell growth by inducing fibronectin expression. 2007 Dec 3
38 16257255 Nicotine stimulates adhesion molecular expression via calcium influx and mitogen-activated protein kinases in human endothelial cells. 2006 Feb 4
39 16644474 Estrogen down-regulates nicotine-induced adhesion molecule expression via nongenomic signal pathway in endothelial cells. 2006 Jun 2
40 15733153 Regulation of extracellular signal-regulated protein kinase signaling in human osteosarcoma cells stimulated with nicotine. 2005 Apr 6
41 15813854 Nicotinic acetylcholine receptor-mediated stimulation of endothelial cells results in the arrest of haematopoietic progenitor cells on endothelium. 2005 Apr 1
42 15447668 MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time. 2004 Oct 4
43 12421819 A functional role for nicotine in Bcl2 phosphorylation and suppression of apoptosis. 2003 Jan 17 1
44 11905997 Nicotine activates the extracellular signal-regulated kinase 1/2 via the alpha7 nicotinic acetylcholine receptor and protein kinase A, in SH-SY5Y cells and hippocampal neurones. 2002 Feb 1
45 9600337 Signalling pathways involved in nicotine regulation of apoptosis of human lung cancer cells. 1998 Apr 3