Protein Name dopamine receptor D2
Organism Homo sapiens
Gene ID 1813
Gene Symbol

DRD2

UniProt P14416 (DRD2_HUMAN), A0A024R3I6 (A0A024R3I6_HUMAN), A0A024R3C5 (A0A024R3C5_HUMAN)
Relationships Total Number of functionally related compound(s) : 660
Total Number of Articles : 1813
Description

dopamine receptor D2

Gene Summary

This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]

synonyms
  • D(2) dopamine receptor
  • dopamine D2 receptor
  • seven transmembrane helix receptor
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Properties