Nicotine

signal transducer and activator of transcription 3 ; Homo sapiens







25 Article(s)
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1 34647621 Nicotine causes alternative polarization of macrophages via Src-mediated STAT3 activation: Potential pathobiological implications. 2022 Feb 3
2 35461327 Exosomal miR-4466 from nicotine-activated neutrophils promotes tumor cell stemness and metabolism in lung cancer metastasis. 2022 May 2
3 33603170 Repurposing dextromethorphan and metformin for treating nicotine-induced cancer by directly targeting CHRNA7 to inhibit JAK2/STAT3/SOX2 signaling. 2021 Mar 2
4 34302119 Correction: Repurposing dextromethorphan and metformin for treating nicotine-induced cancer by directly targeting CHRNA7 to inhibit JAK2/STAT3/SOX2 signaling. 2021 Aug 1
5 34771509 Nicotinic Acetylcholine Receptor Subunit α7 Mediates Cigarette Smoke-Induced PD-L1 Expression in Human Bronchial Epithelial Cells. 2021 Oct 25 1
6 31953160 Nicotine promotes activation of human pancreatic stellate cells through inducing autophagy via α7nAChR-mediated JAK2/STAT3 signaling pathway. 2020 Feb 15 4
7 31956373 Nicotine Upregulates the Level of Mcl-1 through STAT3 in H1299 Cells. 2020 6
8 32976884 Inflection of Akt/mTOR/STAT-3 cascade in TNF-α induced protein 8 mediated human lung carcinogenesis. 2020 Dec 1 1
9 30317657 Nicotine stimulates IL-6 expression by activating the AP-1 and STAT-3 pathways in human endothelial EA.hy926 cells. 2019 Apr 3
10 31835799 The α9 Nicotinic Acetylcholine Receptor Mediates Nicotine-Induced PD-L1 Expression and Regulates Melanoma Cell Proliferation and Migration. 2019 Dec 11 1
11 27709266 Nicotine protects against DSS colitis through regulating microRNA-124 and STAT3. 2017 Feb 8
12 28750889 Reciprocal activation of α5-nAChR and STAT3 in nicotine-induced human lung cancer cell proliferation. 2017 Jul 20 6
13 28766689 Nicotine induces TIPE2 upregulation and Stat3 phosphorylation contributes to cholinergic anti-inflammatory effect. 2017 Sep 7
14 25565665 HIF-2 Inhibition Supresses Inflammatory Responses and Osteoclastic Differentiation in Human Periodontal Ligament Cells. 2015 Jul 1
15 24321995 Carbonic anhydrase IX is associated with early pulmonary spreading of primary colorectal carcinoma and tobacco smoking. 2014 Jul 1
16 24668500 Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic acetylcholine receptor and STAT3. 2014 May 4
17 25259522 A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via α7 nicotinic receptors in human macrophages. 2014 2
18 25295465 Transcriptional regulation of the novel monoamine oxidase renalase: Crucial roles of transcription factors Sp1, STAT3, and ZBP89. 2014 Nov 11 1
19 23717691 Myeloid clusters are associated with a pro-metastatic environment and poor prognosis in smoking-related early stage non-small cell lung cancer. 2013 1
20 22300039 The Yin and Yang of non-neuronal α7-nicotinic receptors in inflammation and autoimmunity. 2012 May 1
21 20943775 α4β2 nicotinic receptors partially mediate anti-inflammatory effects through Janus kinase 2-signal transducer and activator of transcription 3 but not calcium or cAMP signaling. 2011 Jan 2
22 21606497 Tristetraprolin mediates anti-inflammatory effects of nicotine in lipopolysaccharide-stimulated macrophages. 2011 Jul 15 6
23 20106947 Long-term nicotine exposure-induced chemoresistance is mediated by activation of Stat3 and downregulation of ERK1/2 via nAChR and beta-adrenoceptors in human bladder cancer cells. 2010 May 4
24 19741199 Cholinergic agonists regulate JAK2/STAT3 signaling to suppress endothelial cell activation. 2009 Nov 1
25 18448488 Rapid activation of Stat3 and ERK1/2 by nicotine modulates cell proliferation in human bladder cancer cells. 2008 Aug 3