Nicotine

cholinergic receptor nicotinic alpha 5 subunit ; Homo sapiens







91 Article(s)
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1 33539855 Linking the CHRNA5 SNP to drug abuse liability: From circuitry to cellular mechanisms. 2021 Mar 15 1
2 33801584 Genetic Factors Associated with COPD Depend on the Ancestral Caucasian/Amerindian Component in the Mexican Population. 2021 Mar 27 1
3 33879270 Genetics of substance use disorders: a review. 2021 Oct 1
4 34159514 The Intergenerational Transmission of Developmental Nicotine Exposure-Induced Neurodevelopmental Disorder-Like Phenotypes is Modulated by the Chrna5 D397N Polymorphism in Adolescent Mice. 2021 Nov 1
5 34206324 Chr15q25 Genetic Variant rs16969968 Alters Cell Differentiation in Respiratory Epithelia. 2021 Jun 22 2
6 34803779 Genetic Modifiers of Oral Nicotine Consumption in Chrna5 Null Mutant Mice. 2021 5
7 32152934 Association of CHRNA5 Gene Variants with Crack Cocaine Addiction. 2020 Sep 1
8 32184221 β4-Nicotinic Receptors Are Critically Involved in Reward-Related Behaviors and Self-Regulation of Nicotine Reinforcement. 2020 Apr 22 2
9 32738310 Genetic susceptibility to nicotine addiction: Advances and shortcomings in our understanding of the CHRNA5/A3/B4 gene cluster contribution. 2020 Oct 15 1
10 30366711 Relationship of common variants in CHRNA5 with early-onset schizophrenia and executive function. 2019 Apr 1
11 31547418 Nicotinic Acetylcholine Receptor Subunit Alpha-5 Promotes Radioresistance via Recruiting E2F Activity in Oral Squamous Cell Carcinoma. 2019 Sep 12 1
12 28972577 Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence. 2018 Sep 1
13 29573323 The interaction of the Chrna5 D398N variant with developmental nicotine exposure. 2018 Sep 2
14 29993116 CHRNA3 rs1051730 and CHRNA5 rs16969968 polymorphisms are associated with heavy smoking, lung cancer, and chronic obstructive pulmonary disease in a mexican population. 2018 Nov 2
15 30293722 A Human Polymorphism in CHRNA5 Is Linked to Relapse to Nicotine Seeking in Transgenic Rats. 2018 Oct 22 1
16 30453884 Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence. 2018 Nov 20 4
17 30543688 Cholinergic Receptor Nicotinic Alpha 5 (CHRNA5) RNAi is associated with cell cycle inhibition, apoptosis, DNA damage response and drug sensitivity in breast cancer. 2018 2
18 30829278 Nicotinic acetylcholine receptor gene polymorphism is not associated with tobacco-related oral squamous cell carcinoma. 2018 Oct-Dec 1
19 29172281 SNP rs16969968 as a Strong Predictor of Nicotine Dependence and Lung Cancer Risk in a North Indian Population 2017 Nov 26 1
20 26239294 Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans. 2016 May 3
21 26751916 CHRNA5/CHRNA3 Locus Associates with Increased Mortality among Smokers. 2016 Aug 1
22 26771213 Exome Array Analysis Identifies a Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease. 2016 Jul 1 1
23 26997181 CHRNA5/A3/B4 Variant rs3743078 and Nicotine-Related Phenotypes: Indirect Effects Through Nicotine Craving. 2016 Mar 2
24 27127891 Association Between CHRNA3 and CHRNA5 Nicotine Receptor Subunit Gene Variants and Nicotine Dependence in an Isolated Populationof Kashubians in Poland. 2016 Apr 29 2
25 27698409 Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele. 2016 Oct 4 1
26 25745024 A powerful nonparametric statistical framework for family-based association analyses. 2015 May 1
27 25948103 A CHRNA5 Smoking Risk Variant Decreases the Aversive Effects of Nicotine in Humans. 2015 Nov 2
28 25950378 Effect of the rs1051730-rs16969968 variant and smoking cessation treatment: a meta-analysis. 2015 1
29 26142345 Genetic variation (CHRNA5), medication (combination nicotine replacement therapy vs. varenicline), and smoking cessation. 2015 Sep 1 1
30 26220977 A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence. 2015 Oct 15 5
31 26228411 Examining gene-environment interactions in comorbid depressive and disruptive behavior disorders using a Bayesian approach. 2015 Sep 1
32 27350810 Genetic influences on nicotinic α5 receptor (CHRNA5) CpG methylation and mRNA expression in brain and adipose tissue. 2015 1
33 24033696 Pharmacotherapy effects on smoking cessation vary with nicotine metabolism gene (CYP2A6). 2014 Jan 1
34 24682045 Identification of CHRNA5 rare variants in African-American heavy smokers. 2014 Jun 1
35 24804708 Functional characterization improves associations between rare non-synonymous variants in CHRNB4 and smoking behavior. 2014 1
36 24934182 CHRNA5 variants moderate the effect of nicotine deprivation on a neural index of cognitive control. 2014 Sep 3
37 25233467 Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma. 2014 2
38 25297392 An association study on the CHRNA5/A3/B4 gene cluster, smoking and psoriasis vulgaris. 2014 Dec 2
39 25384568 Hippocampal changes produced by overexpression of the human CHRNA5/A3/B4 gene cluster may underlie cognitive deficits rescued by nicotine in transgenic mice. 2014 Nov 11 1
40 22884254 Association of nicotine dependence susceptibility gene, CHRNA5, with Parkinson's disease age at onset: gene and smoking status interaction. 2013 Jan 1
41 23308091 A complex interplay between personality domains, marital status and a variant in CHRNA5 on the risks of cocaine, nicotine dependences and cocaine-induced paranoia. 2013 1
42 23458267 Examination of rare missense variants in the CHRNA5-A3-B4 gene cluster to level of response to alcohol in the San Diego Sibling Pair study. 2013 Aug 1
43 23692359 CHRNA5-A3-B4 genetic variants alter nicotine intake and interact with tobacco use to influence body weight in Alaska Native tobacco users. 2013 Oct 5
44 23875064 Scrutiny of the CHRNA5-CHRNA3-CHRNB4 smoking behavior locus reveals a novel association with alcohol use in a Finnish population based study. 2013 1
45 24062692 Nicotinic acetylcholine receptors mediate lung cancer growth. 2013 1
46 24227714 Medial habenula output circuit mediated by α5 nicotinic receptor-expressing GABAergic neurons in the interpeduncular nucleus. 2013 Nov 13 1
47 25214750 Genomics and personalized medicine: CHRNA5-CHRNA3-CHRNB4 and smoking cessation treatment. 2013 Dec 1
48 21764527 Association between CHRNA5 genetic variation at rs16969968 and brain reactivity to smoking images in nicotine dependent women. 2012 Jan 1 2
49 21955800 The polymorphism of the CHRNA5 gene and the strength of nicotine addiction in lung cancer and COPD patients. 2012 Mar 4
50 21968931 The CHRNA5-A3-B4 gene cluster in nicotine addiction. 2012 Sep 1