Protein Name | corticotropin releasing hormone |
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Organism | Rattus norvegicus |
Gene ID | 81648 |
Gene Symbol | Crh |
UniProt | P01143 (CRF_RAT) |
Relationships |
Total Number of functionally related compound(s) :
573
Total Number of Articles : 1303 |
Description |
corticotropin releasing hormone |
Gene Summary |
Enables corticotropin-releasing hormone receptor 1 binding activity and corticotropin-releasing hormone receptor 2 binding activity. Involved in several processes, including regulation of ion transport; regulation of secretion by cell; and response to glucocorticoid. Located in several cellular components, including extracellular space; perikaryon; and varicosity. Used to study hypoglycemia and obesity. Biomarker of several diseases, including alcohol use disorder; cerebrovascular disease (multiple); extrahepatic cholestasis; sciatic neuropathy; and withdrawal disorder. Human ortholog(s) of this gene implicated in obesity and panic disorder. Orthologous to human CRH (corticotropin releasing hormone). [provided by Alliance of Genome Resources, Apr 2022] |
synonyms |
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Properties | |