Nicotine

cholinergic receptor nicotinic alpha 4 subunit ; Homo sapiens







397 Article(s)
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1 34253876 Levo-tetrahydropalmatine inhibits α4β2 nicotinic receptor response to nicotine in cultured SH-EP1 cells. 2022 Apr 1
2 34939632 Gas phase protonated nicotine is a mixture of pyridine- and pyrrolidine-protonated conformers: implications for its native structure in the nicotinic acetylcholine receptor. 2022 Mar 9 4
3 35044626 Structural Plasticity of Dopaminergic Neurons Requires the Activation of the D3R-nAChR Heteromer and the PI3K-ERK1/2/Akt-Induced Expression of c-Fos and p70S6K Signaling Pathway. 2022 Apr 3
4 35111269 The Natural Compound Dehydrocrenatidine Attenuates Nicotine-Induced Stemness and Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma by Regulating a7nAChR-Jak2 Signaling Pathways. 2022 1
5 35234149 Interactions between 2'-fluoro-(carbamoylpyridinyl)deschloroepibatidine analogues and acetylcholine-binding protein inform on potent antagonist activity against nicotinic receptors. 2022 Mar 1 1
6 35565402 Reducing Chemotherapy-Induced DNA Damage via nAChR-Mediated Redox Reprograming-A New Mechanism for SCLC Chemoresistance Boosted by Nicotine. 2022 May 2 1
7 33284031 Nicotine: A Targeted Therapy for Epilepsy Due to nAChR Gene Variants. 2021 Apr 3
8 33380469 α3* Nicotinic Acetylcholine Receptors in the Habenula-Interpeduncular Nucleus Circuit Regulate Nicotine Intake. 2021 Feb 24 1
9 34001335 Nicotinic receptor targeting in physiological and environmental vulnerability: A whole of biosphere perspective. 2021 Aug 1 1
10 34273166 Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress and extracellular vesicle release in vascular smooth muscle cells. 2021 Jul 17 2
11 34360698 Simulations of Promising Indolizidine-α6-β2 Nicotinic Acetylcholine Receptor Complexes. 2021 Jul 25 1
12 34523332 Design, Synthesis, and Activity of an α-Conotoxin LtIA Fluorescent Analogue. 2021 Oct 6 1
13 34618202 Cross-species evidence that nicotine widens the attentional window. 2021 Dec 1
14 34938964 Biophysical characterization of lynx-nicotinic receptor interactions using atomic force microscopy. 2021 Dec 1
15 34946630 Synthetic Methods for the Preparation of Conformationally Restricted Analogues of Nicotine. 2021 Dec 13 1
16 31399700 Cocaine potently blocks neuronal α3β4 nicotinic acetylcholine receptors in SH-SY5Y cells. 2020 Feb 1
17 31887290 Characterization of AN6001, a positive allosteric modulator of α6β2-containing nicotinic acetylcholine receptors. 2020 Apr 1
18 31925927 Nicotinic acetylcholine receptor signaling regulates inositol-requiring enzyme 1α activation to protect β-cells against terminal unfolded protein response under irremediable endoplasmic reticulum stress. 2020 Jul 1
19 31956359 Nicotinic-nAChR signaling mediates drug resistance in lung cancer. 2020 2
20 32044666 α7 nAChRs expressed on antigen presenting cells are insensitive to the conventional antagonists α-bungarotoxin and methyllycaconitine. 2020 Apr 1
21 32113032 Advances in the In vitro and In vivo pharmacology of Alpha4beta2 nicotinic receptor positive allosteric modulators. 2020 May 15 1
22 32451953 Cholinergic Receptors and Addiction. 2020 2
23 32659920 Dopamine D3 Receptor Heteromerization: Implications for Neuroplasticity and Neuroprotection. 2020 Jul 9 1
24 32707263 The role of nicotinic acetylcholine receptors in alcohol-related behaviors. 2020 Oct 1
25 32957649 Low-Dose Nicotine Activates EGFR Signaling via α5-nAChR and Promotes Lung Adenocarcinoma Progression. 2020 Sep 17 4
26 33022581 Increased thalamic volume and decreased thalamo-precuneus functional connectivity are associated with smoking relapse. 2020 2
27 33184579 Cholinergic Activation of Primary Human Derived Intestinal Epithelium Does Not Ameliorate TNF-α Induced Injury. 2020 Oct 1
28 33253222 Component of nicotine-induced intracellular calcium elevation mediated through α3- and α5-containing nicotinic acetylcholine receptors are regulated by cyclic AMP in SH-SY 5Y cells. 2020 2
29 29637850 NAChR α4β2 Subtype and their Relation with Nicotine Addiction, Cognition, Depression and Hyperactivity Disorder. 2019 2
30 29881944 (E)-Nicotinaldehyde O-Cinnamyloxime, a Nicotine Analog, Attenuates Neuronal Cells Death Against Rotenone-Induced Neurotoxicity. 2019 Feb 1
31 30137518 Nicotinic Acetylcholine Receptor Ligands, Cognitive Function, and Preclinical Approaches to Drug Discovery. 2019 Feb 18 2
32 30550855 TRPC channels mediated calcium entry is required for proliferation of human airway smooth muscle cells induced by nicotine-nAChR. 2019 Mar 3
33 30552041 Effects of nicotine and atomoxetine on brain function during response inhibition. 2019 Dec 3
34 30718376 Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. 2019 Jun 3 1
35 30772268 The novel hybrid agonist HyNDA-1 targets the D3R-nAChR heteromeric complex in dopaminergic neurons. 2019 May 1
36 30809122 CHRNA2 and Nocturnal Frontal Lobe Epilepsy: Identification and Characterization of a Novel Loss of Function Mutation. 2019 1
37 30874860 Effects of nicotine on smooth pursuit eye movements in healthy non-smokers. 2019 Jul 2
38 31062355 Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor. 2019 Aug 1
39 31078264 α4β2 nicotinic acetylcholine receptor downregulates D3 dopamine receptor expression through protein kinase C activation. 2019 Jun 30 1
40 31130483 Identification of the Initial Steps in Signal Transduction in the α4β2 Nicotinic Receptor: Insights from Equilibrium and Nonequilibrium Simulations. 2019 Jul 2 1
41 31221718 Discovery of an intrasubunit nicotinic acetylcholine receptor-binding site for the positive allosteric modulator Br-PBTC. 2019 Aug 9 1
42 31518499 Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor. 2019 Oct 9 1
43 28726253 α9- and α7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line. 2018 Jun 2
44 28762314 Insights Into Nicotinic Receptor Signaling in Nicotine Addiction: Implications for Prevention and Treatment. 2018 2
45 28859996 Nicotine and networks: Potential for enhancement of mood and cognition in late-life depression. 2018 Jan 2
46 29110618 Cognitive Effects of Nicotine: Recent Progress. 2018 1
47 29215705 Activation of fibroblasts by nicotine promotes the epithelial-mesenchymal transition and motility of breast cancer cells. 2018 Jun 1
48 29618714 Nicotine and methyl vinyl ketone, major components of cigarette smoke extracts, increase protective amyloid-β peptides in cells harboring amyloid-β precursor protein. 2018 3
49 29619740 Nicotine Modulates Mitochondrial Dynamics in Hippocampal Neurons. 2018 Dec 3
50 29621993 Cholinergic receptor nicotinic alpha 5 subunit polymorphisms are associated with smoking cessation success in women. 2018 Apr 5 2