Protein Name cannabinoid receptor 1
Organism Rattus norvegicus
Gene ID 25248
Gene Symbol

Cnr1

UniProt P20272 (CNR1_RAT)
Relationships Total Number of functionally related compound(s) : 570
Total Number of Articles : 1380
Description

cannabinoid receptor 1

Gene Summary

Enables cannabinoid receptor activity. Involved in several processes, including positive regulation of acute inflammatory response; regulation of secretion by cell; and response to alkaloid. Located in membrane raft and plasma membrane. Colocalizes with intracellular membrane-bounded organelle. Used to study several diseases, including Parkinsonism; diabetic neuropathy; impotence; obesity; and peptic ulcer disease. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in obesity; schizophrenia; and type 2 diabetes mellitus. Orthologous to human CNR1 (cannabinoid receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cannabinoid receptor 1
  • Cannabinoid CB1 receptor
  • brain-type cannabinoid receptor
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Properties