| Protein Name | tyrosine hydroxylase |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 25085 |
| Gene Symbol | Th |
| UniProt | P04177 (TY3H_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
552
Total Number of Articles : 1071 |
Description |
tyrosine hydroxylase |
| Gene Summary |
Enables several functions, including cation binding activity; oxygen binding activity; and tyrosine 3-monooxygenase activity. Involved in several processes, including aminergic neurotransmitter loading into synaptic vesicle; carboxylic acid metabolic process; and cellular response to nicotine. Located in several cellular components, including cytoplasmic vesicle; perikaryon; and terminal bouton. Used to study Parkinson's disease. Biomarker of several diseases, including brain disease (multiple); hyperprolactinemia; polycystic ovary syndrome; portal hypertension; and uremia. Human ortholog(s) of this gene implicated in Parkinson's disease; Parkinsonism; heroin dependence; hypertension; and obesity. Orthologous to human TH (tyrosine hydroxylase). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |