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1904 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 ERCC excision repair 1, endonuclease non-catalytic subunit ERCC1_HUMAN ERCC1 Homo sapiens 2067 239 302
2 BRCA1 DNA repair associated BRCA1_HUMAN BRCA1 Homo sapiens 672 696 294
3 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 172
4 poly(ADP-ribose) polymerase 1 PARP1_HUMAN PARP1 Homo sapiens 142 2571 125
5 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 116
6 BRCA2 DNA repair associated BRCA2_HUMAN BRCA2 Homo sapiens 675 305 91
7 CD274 molecule PD1L1_HUMAN CD274 Homo sapiens 29126 1115 79
8 spindlin 1 SPIN1_HUMAN SPIN1 Homo sapiens 10927 3123 62
9 solute carrier family 31 member 1 COPT1_HUMAN SLC31A1 Homo sapiens 1317 119 55
10 X-ray repair cross complementing 1 XRCC1_HUMAN XRCC1 Homo sapiens 7515 281 55
11 erb-b2 receptor tyrosine kinase 2 ERBB2_HUMAN ERBB2 Homo sapiens 2064 2723 50
12 ERCC excision repair 2, TFIIH core complex helicase subunit ERCC2_HUMAN ERCC2 Homo sapiens 2068 167 48
13 zinc finger protein 77 ZNF77_HUMAN ZNF77 Homo sapiens 58492 224 42
14 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 39
15 programmed cell death 1 PDCD1_HUMAN PDCD1 Homo sapiens 5133 637 36
16 albumin ALBU_HUMAN ALB Homo sapiens 213 5631 36
17 erythropoietin EPO_HUMAN EPO Homo sapiens 2056 1312 35
18 mucin 16, cell surface associated MUC16_HUMAN MUC16 Homo sapiens 94025 408 31
19 hydroxyacid oxidase 1 HAOX1_HUMAN HAO1 Homo sapiens 54363 931 31
20 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 31
21 glutathione S-transferase pi 1 GSTP1_HUMAN GSTP1 Homo sapiens 2950 703 30
22 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 30
23 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 26
24 ATPase copper transporting alpha ATP7A_HUMAN ATP7A Homo sapiens 538 149 25
25 BCL2 apoptosis regulator BCL2_HUMAN BCL2 Homo sapiens 596 4403 24
26 ATPase copper transporting beta ATP7B_HUMAN ATP7B Homo sapiens 540 124 24
27 ribonucleotide reductase catalytic subunit M1 RIR1_HUMAN RRM1 Homo sapiens 6240 316 23
28 caveolin 1 CAV1_HUMAN CAV1 Homo sapiens 857 2406 22
29 ALK receptor tyrosine kinase ALK_HUMAN ALK Homo sapiens 238 603 22
30 latexin LXN_HUMAN LXN Homo sapiens 56925 5329 20
31 ATP binding cassette subfamily C member 2 MRP2_HUMAN ABCC2 Homo sapiens 1244 684 20
32 ERCC excision repair 4, endonuclease catalytic subunit XPF_HUMAN ERCC4 Homo sapiens 2072 87 19
33 translocase of inner mitochondrial membrane 8A TIM8A_HUMAN TIMM8A Homo sapiens 1678 214 19
34 ERCC excision repair 5, endonuclease ERCC5_HUMAN ERCC5 Homo sapiens 2073 76 18
35 collagen type XI alpha 2 chain COBA2_HUMAN COL11A2 Homo sapiens 1302 794 18
36 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 17
37 methylenetetrahydrofolate reductase MTHR_HUMAN MTHFR Homo sapiens 4524 396 15
38 protein phosphatase 4 catalytic subunit PP4C_HUMAN PPP4C Homo sapiens 5531 1132 15
39 glutathione S-transferase kappa 1 GSTK1_HUMAN GSTK1 Homo sapiens 373156 1019 15
40 CDP-diacylglycerol synthase 1 CDS1_HUMAN CDS1 Homo sapiens 1040 831 15
41 DNA polymerase iota POLI_HUMAN POLI Homo sapiens 11201 1165 14
42 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 14
43 5'-nucleotidase, cytosolic II 5NTC_HUMAN NT5C2 Homo sapiens 22978 912 14
44 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 14
45 thymidylate synthetase TYSY_HUMAN TYMS Homo sapiens 7298 800 14
46 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 14
47 estrogen receptor 1 ESR1_HUMAN ESR1 Homo sapiens 2099 3003 14
48 nuclear factor kappa B subunit 1 NFKB1_HUMAN NFKB1 Homo sapiens 4790 4834 14
49 glutathione S-transferase mu 1 GSTM1_HUMAN GSTM1 Homo sapiens 2944 517 14
50 SCLC1 - SCLC1 Homo sapiens 7864 68 14