| 1 |
35005470 | First successful case of platinum-based chemotherapy for neuroendocrine prostate cancer with BRCA2 and PTEN alterations. | 2022 Jan |
2 |
| 2 |
35385581 | Templated insertions are associated specifically with BRCA2 deficiency and overall survival in advanced ovarian cancer. | 2022 Apr 6 |
1 |
| 3 |
32885350 | FoundationOne® CDx gene profiling in Japanese pancreatic ductal adenocarcinoma patients: a single-institution experience. | 2021 Apr |
1 |
| 4 |
32965028 | Impact of DNA damage repair defects and aggressive variant features on response to carboplatin-based chemotherapy in metastatic castration-resistant prostate cancer. | 2021 Jan 15 |
2 |
| 5 |
33091561 | A meta-analysis of reversion mutations in BRCA genes identifies signatures of DNA end-joining repair mechanisms driving therapy resistance. | 2021 Jan |
1 |
| 6 |
33375991 | Characterizing TP53 mutations in ovarian carcinomas with and without concurrent BRCA1 or BRCA2 mutations. | 2021 Mar |
1 |
| 7 |
33524400 | Genomic Features and Classification of Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma. | 2021 May |
1 |
| 8 |
33608381 | Treatment-emergent neuroendocrine prostate cancer with a germline BRCA2 mutation: identification of a candidate reversion mutation associated with platinum/PARP-inhibitor resistance. | 2021 Feb |
1 |
| 9 |
33619265 | Longitudinal and multi-tissue molecular diagnostics track somatic BRCA2 reversion mutations that correct the open reading frame of germline alteration upon clinical relapse. | 2021 Feb 22 |
1 |
| 10 |
33904759 | Distinct Response to Platinum-Based Chemotherapy among Patients with Metastatic Castration-Resistant Prostate Cancer Harboring Alterations in Genes Involved in Homologous Recombination. | 2021 Sep |
1 |
| 11 |
33990090 | Use of Circulating Tumor DNA for the Clinical Management of Metastatic Castration-Resistant Prostate Cancer: A Multicenter, Real-World Study. | 2021 May 14 |
1 |
| 12 |
34021944 | Homologous Recombination Deficiency: Cancer Predispositions and Treatment Implications. | 2021 Sep |
1 |
| 13 |
34086042 | Concordance of DNA Repair Gene Mutations in Paired Primary Prostate Cancer Samples and Metastatic Tissue or Cell-Free DNA. | 2021 Jun 4 |
1 |
| 14 |
34091215 | Combined modality therapy including cytoreductive surgery and heated intraperitoneal chemotherapy for synchronous low volume peritoneal carcinomatosis from adenocarcinoma of the tail of pancreas in a BRCA-2 carrier resulting in long-term disease-free survival: A case report. | 2021 Jun |
1 |
| 15 |
34258530 | Prominent response to platinum-based chemotherapy in a patient with BRCA2 mutant-neuroendocrine prostate cancer and MDM2 amplification. | 2021 Jul |
1 |
| 16 |
34258531 | Editorial Comment to Prominent response to platinum-based chemotherapy in a patient with BRCA2 mutant-neuroendocrine prostate cancer and MDM2 amplification. | 2021 Jul |
1 |
| 17 |
34302857 | Association of somatic mutations in BRCA2 BRC domain with chemotherapy sensitivity and survival in high grade serous ovarian cancer. | 2021 Sep 1 |
2 |
| 18 |
34309133 | Rapid Progression of Metastatic Pancreatic Adenocarcinoma During Platinum-Based Therapy in a Patient Harboring a Pathogenic BRCA2 Germline Variant. | 2021 Nov |
5 |
| 19 |
34367927 | Mechanisms of acquired resistance of BRCA1/2-driven tumors to platinum compounds and PARP inhibitors. | 2021 Jul 24 |
1 |
| 20 |
34367977 | Analysis of Adaptive Olaparib Resistance Effects on Cisplatin Sensitivity in Triple Negative Breast Cancer Cells. | 2021 |
1 |
| 21 |
34425813 | A novel germline BRCA2 mutation in a Chinese patient with prostate cancer sensitive to platinum chemotherapy: a case report. | 2021 Aug 23 |
1 |
| 22 |
34697207 | Catastrophic chemotherapy toxicity leading to diagnosis of Fanconi anaemia due to FANCD1/BRCA2 during adulthood: description of an emerging phenotype. | 2021 Oct 25 |
1 |
| 23 |
34778033 | BRCA1 Versus BRCA2 and PARP Inhibitors Efficacy in Solid Tumors:A Meta-Analysis of Randomized Controlled Trials. | 2021 |
1 |
| 24 |
31787751 | Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation. | 2020 Feb |
2 |
| 25 |
32071115 | Detection of Molecular Signatures of Homologous Recombination Deficiency in Prostate Cancer with or without BRCA1/2 Mutations. | 2020 Jun 1 |
1 |
| 26 |
32171277 | Polyclonal BRCA2 mutations following carboplatin treatment confer resistance to the PARP inhibitor rucaparib in a patient with mCRPC: a case report. | 2020 Mar 14 |
1 |
| 27 |
32699032 | Clinical BRCA1/2 Reversion Analysis Identifies Hotspot Mutations and Predicted Neoantigens Associated with Therapy Resistance. | 2020 Oct |
1 |
| 28 |
32711554 | BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer. | 2020 Jul 25 |
1 |
| 29 |
32789480 | Effect of Adjuvant Paclitaxel and Carboplatin on Survival in Women With Triple-Negative Breast Cancer: A Phase 3 Randomized Clinical Trial. | 2020 Sep 1 |
2 |
| 30 |
32816949 | A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination-deficient Pancreatic Cancer. | 2020 Oct 15 |
1 |
| 31 |
32861273 | Veliparib with carboplatin and paclitaxel in BRCA-mutated advanced breast cancer (BROCADE3): a randomised, double-blind, placebo-controlled, phase 3 trial. | 2020 Oct |
1 |
| 32 |
32884538 | Excellent Response to Olaparib in a Patient with Metastatic Pancreatic Adenocarcinoma with Germline BRCA1 Mutation after Progression on FOLFIRINOX: Case Report and Literature Review. | 2020 May-Aug |
1 |
| 33 |
33194641 | Case Report: Co-Existence of BRCA2 and PALB2 Germline Mutations in Familial Prostate Cancer With Solitary Lung Metastasis. | 2020 |
1 |
| 34 |
33357097 | The BRCA2 p.N372 H i.a.1342A>C Could Regulate the Sensitivity of Ovarian Cancer Cells to Platinum-Based Drugs. | 2020 Jan-Dec |
4 |
| 35 |
30270052 | Tumor Lysis Syndrome After Platinum-based Chemotherapy in Castration-resistant Prostate Cancer With a BRCA2 Mutation: A Case Report. | 2019 Feb |
1 |
| 36 |
30871108 | BRCA2 and Other DDR Genes in Prostate Cancer. | 2019 Mar 12 |
1 |
| 37 |
31320873 | Somatic BRCA2 Mutation-Positive Concurrent Accessory Male Breast Cancer (BC) and Non-Small Cell Lung Cancer (NSCLC): Excellent Efficacy of Palbociclib, Fulvestrant and Leuprolide in Platinum-Exposed and Endocrine-Refractory BC Associated with Cyclin D1 and FGFR1 Amplification and of Carboplatin, Paclitaxel and Radiation in NSCLC. | 2019 May-Aug |
1 |
| 38 |
31409079 | Effectiveness of Neoadjuvant Therapy with Platinum-Based Agents for Patients with BRCA1 and BRCA2 Germline Mutations - A Retrospective Analysis of Breast Cancer Patients Treated at MMCI Brno. | 2019 Summer |
1 |
| 39 |
31499327 | Functional profiling of nucleotide Excision repair in breast cancer. | 2019 Oct |
1 |
| 40 |
31565603 | Molecular Testing Identifies Determinants of Exceptional Response and Guides Precision Therapy in a Patient with Lethal, Treatment-emergent Neuroendocrine Prostate Cancer. | 2019 Jul 22 |
2 |
| 41 |
31591549 | Towards precision oncology in advanced prostate cancer. | 2019 Nov |
1 |
| 42 |
31604666 | Clinical factors associated with prolonged response and survival under olaparib as maintenance therapy in BRCA mutated ovarian cancers. | 2019 Nov |
2 |
| 43 |
29066501 | Knockdown of BRCA2 enhances cisplatin and cisplatin-induced autophagy in ovarian cancer cells. | 2018 Jan |
6 |
| 44 |
29309945 | BRCA1/BRCA2 Germline Mutation Carriers and Sporadic Pancreatic Ductal Adenocarcinoma. | 2018 Apr |
2 |
| 45 |
29331492 | Prognostic Value of the Expression of DNA Repair-Related Biomarkers Mediated by Alcohol in Gastric Cancer Patients. | 2018 Feb |
1 |
| 46 |
29541174 | Non-small cell neuroendocrine carcinoma of the ovary in a BRCA2-germline mutation carrier: A case report and brief review of the literature. | 2018 Apr |
1 |
| 47 |
29617652 | Multifaceted Impact of MicroRNA 493-5p on Genome-Stabilizing Pathways Induces Platinum and PARP Inhibitor Resistance in BRCA2-Mutated Carcinomas. | 2018 Apr 3 |
3 |
| 48 |
29729664 | Complete response to orally administered melphalan in malignant pleural effusion from an occult female genital organ primary neoplasm with BRCA1/2 mutations: a case report. | 2018 May 6 |
1 |
| 49 |
29802286 | Mutations in BRCA1, BRCA2, and PALB2, and a panel of 50 cancer-associated genes in pancreatic ductal adenocarcinoma. | 2018 May 25 |
1 |
| 50 |
30111871 | BRCA1 and BRCA2 mRNA-expression prove to be of clinical impact in ovarian cancer. | 2018 Sep |
1 |