| 1 |
35093146 | Neoantigens and the tumor microenvironment play important roles in the prognosis of high-grade serous ovarian cancer. | 2022 Jan 29 |
4 |
| 2 |
33669671 | Effect of Oxaliplatin, Olaparib and LY294002 in Combination on Triple-Negative Breast Cancer Cells. | 2021 Feb 19 |
1 |
| 3 |
33827148 | Role of FOXO protein's abnormal activation through PI3K/AKT pathway in platinum resistance of ovarian cancer. | 2021 Jun |
1 |
| 4 |
34365218 | Predicting response to platinum and non-platinum drugs through bioluminescence resonance energy transfer (BRET) based bio-molecular interactions in platinum resistant epithelial ovarian cancer. | 2021 Nov |
1 |
| 5 |
34681173 | Activity of New Synthetic (2-Chloroethylthio)-1,4-naphthoquinones in Prostate Cancer Cells. | 2021 Sep 22 |
1 |
| 6 |
34717622 | Quantitative phosphoproteomic analysis reveals chemoresistance-related proteins and signaling pathways induced by rhIL-6 in human osteosarcoma cells. | 2021 Oct 30 |
1 |
| 7 |
32083163 | Results of an abbreviated phase II study of AKT inhibitor MK-2206 in the treatment of recurrent platinum-resistant high grade serous ovarian, fallopian tube, or primary peritoneal carcinoma (NCT 01283035). | 2020 May |
1 |
| 8 |
32642416 | Platinum complexes of curcumin delivered by dual-responsive polymeric nanoparticles improve chemotherapeutic efficacy based on the enhanced anti-metastasis activity and reduce side effects. | 2020 Jun |
1 |
| 9 |
32703189 | A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway. | 2020 Jul 23 |
1 |
| 10 |
32934772 | Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer. | 2020 Sep 1 |
1 |
| 11 |
29910616 | Inhibitory effect of Au@Pt-NSs on proliferation, migration, and invasion of EJ bladder carcinoma cells: involvement of cell cycle regulators, signaling pathways, and transcription factor-mediated MMP-9 expression. | 2018 |
1 |
| 12 |
30364051 | Toxicological Implications of Platinum Nanoparticle Exposure: Stimulation of Intracellular Stress, Inflammatory Response, and Akt Signaling In Vitro. | 2018 |
1 |
| 13 |
28139737 | Histone H4 expression is cooperatively maintained by IKKβ and Akt1 which attenuates cisplatin-induced apoptosis through the DNA-PK/RIP1/IAPs signaling cascade. | 2017 Jan 31 |
1 |
| 14 |
28342452 | Contribution of genetic factors to platinum-based chemotherapy sensitivity and prognosis of non-small cell lung cancer. | 2017 Jan - Mar |
1 |
| 15 |
29262602 | Dihydroartemisinin inhibits EMT induced by platinum-based drugs via Akt-Snail pathway. | 2017 Nov 28 |
1 |
| 16 |
27196780 | Dual mTORC1/2 Inhibition as a Novel Strategy for the Resensitization and Treatment of Platinum-Resistant Ovarian Cancer. | 2016 Jul |
2 |
| 17 |
27517495 | Carcinoma-associated fibroblasts affect sensitivity to oxaliplatin and 5FU in colorectal cancer cells. | 2016 Sep 13 |
1 |
| 18 |
27677586 | Differential network analysis from cross-platform gene expression data. | 2016 Sep 28 |
1 |
| 19 |
25115278 | Anti-tumour activity of phosphoinositide-3-kinase antagonist AEZS-126 in models of ovarian cancer. | 2015 Jan |
1 |
| 20 |
25462204 | Brown algae phlorotannins enhance the tumoricidal effect of cisplatin and ameliorate cisplatin nephrotoxicity. | 2015 Feb |
1 |
| 21 |
25519148 | Preclinical Efficacy for AKT Targeting in Clear Cell Carcinoma of the Ovary. | 2015 Apr |
1 |
| 22 |
26039708 | Somatic Copy Number Abnormalities and Mutations in PI3K/AKT/mTOR Pathway Have Prognostic Significance for Overall Survival in Platinum Treated Locally Advanced or Metastatic Urothelial Tumors. | 2015 |
1 |
| 23 |
26497682 | A putative biomarker signature for clinically effective AKT inhibition: correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway. | 2015 Dec 8 |
4 |
| 24 |
26579492 | Preventing Damage Limitation: Targeting DNA-PKcs and DNA Double-Strand Break Repair Pathways for Ovarian Cancer Therapy. | 2015 |
1 |
| 25 |
26585822 | Genetic variations in the PI3K/AKT pathway predict platinum-based neoadjuvant chemotherapeutic sensitivity in squamous cervical cancer. | 2015 Dec 15 |
4 |
| 26 |
26675567 | Potential targets for ovarian clear cell carcinoma: a review of updates and future perspectives. | 2015 |
1 |
| 27 |
25281495 | Somatic copy number alterations predict response to platinum therapy in epithelial ovarian cancer. | 2014 Dec |
2 |
| 28 |
23408298 | A phase 1 study of everolimus plus docetaxel plus cisplatin as induction chemotherapy for patients with locally and/or regionally advanced head and neck cancer. | 2013 May 15 |
1 |
| 29 |
23877012 | Perifosine, an AKT inhibitor, modulates ovarian cancer cell line sensitivity to cisplatin-induced growth arrest. | 2013 Oct |
1 |
| 30 |
22322152 | E Platinum, a newly synthesized platinum compound, induces autophagy via inhibiting phosphorylation of mTOR in gastric carcinoma BGC-823 cells. | 2012 Apr 5 |
1 |
| 31 |
22484552 | Evaluation of 2-deoxy-2-[18F]fluoro-D-glucose- and 3'-deoxy-3'-[18F]fluorothymidine-positron emission tomography as biomarkers of therapy response in platinum-resistant ovarian cancer. | 2012 Dec |
2 |
| 32 |
22901187 | Genetic variants in the PI3K/PTEN/AKT/mTOR pathway predict platinum-based chemotherapy response of advanced non-small cell lung cancers in a Chinese population. | 2012 |
2 |
| 33 |
22992944 | Downregulation of AKT reverses platinum resistance of human ovarian cancers in vitro. | 2012 Dec |
4 |
| 34 |
20405296 | Induction of programmed cell death by inhibition of AKT with the alkylphosphocholine perifosine in in vitro models of platinum sensitive and resistant ovarian cancers. | 2011 Mar |
1 |
| 35 |
20447721 | PI3K/PTEN/AKT/mTOR pathway genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinum-based chemotherapy. | 2011 Jan |
1 |
| 36 |
21057220 | Prognostic effect of epidermal growth factor receptor gene mutations and the aberrant phosphorylation of Akt and ERK in ovarian cancer. | 2011 Jan 1 |
1 |
| 37 |
22131882 | DNA-PK mediates AKT activation and apoptosis inhibition in clinically acquired platinum resistance. | 2011 Nov |
6 |
| 38 |
20032415 | The Akt and ERK activation by platinum-based chemotherapy in ovarian cancer is associated with favorable patient outcome. | 2009 Nov |
1 |
| 39 |
15501963 | Phospho-Akt overexpression in non-small cell lung cancer confers significant stage-independent survival disadvantage. | 2004 Oct 15 |
1 |