Platinum

KRAS proto-oncogene, GTPase ; Homo sapiens







31 Article(s)
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1 34419376 Near-Complete Response to Combined Pembrolizumab and Platinum-Doublet in a Patient With STK11/KRAS Mutated Advanced Lung Adenocarcinoma. 2022 Mar 1
2 35443055 MAPK pathway genetic alterations are associated with prolonged overall survival in low-grade serous ovarian carcinoma. 2022 Apr 20 2
3 35565194 KRAS Mutations Impact Clinical Outcome in Metastatic Non-Small Cell Lung Cancer. 2022 Apr 20 2
4 33099543 ctDNA in Neuroendocrine Carcinoma of Gastroenteropancreatic Origin or of Unknown Primary: The CIRCAN-NEC Pilot Study. 2021 1
5 34824550 Identification of Three Potential Prognostic Genes in Platinum-Resistant Ovarian Cancer via Integrated Bioinformatics Analysis. 2021 1
6 31332704 Clinical outcomes to pemetrexed-based versus non-pemetrexed-based platinum doublets in patients with KRAS-mutant advanced non-squamous non-small cell lung cancer. 2020 May 1
7 32751518 Predicting the Role of DNA Polymerase β Alone or with KRAS Mutations in Advanced NSCLC Patients Receiving Platinum-Based Chemotherapy. 2020 Jul 30 2
8 32753889 Sequential Whole Exome Sequencing Reveals Somatic Mutations Associated with Platinum Response in NSCLC. 2020 1
9 32891532 Pancreatic neuroendocrine carcinoma G3 may be heterogeneous and could be classified into two distinct groups. 2020 Oct 3
10 31597567 Tracking longitudinal genetic changes of circulating tumor DNA (ctDNA) in advanced Lung adenocarcinoma treated with chemotherapy. 2019 Oct 10 1
11 31600989 KRAS Mutations Predict Response and Outcome in Advanced Lung Adenocarcinoma Patients Receiving First-Line Bevacizumab and Platinum-Based Chemotherapy. 2019 Oct 9 1
12 29089357 Effects of Co-occurring Genomic Alterations on Outcomes in Patients with KRAS-Mutant Non-Small Cell Lung Cancer. 2018 Jan 15 1
13 30149143 Metformin Enhances Cisplatin-Induced Apoptosis and Prevents Resistance to Cisplatin in Co-mutated KRAS/LKB1 NSCLC. 2018 Nov 1
14 30217639 KRAS-specific Amino Acid Substitutions are Associated With Different Responses to Chemotherapy in Advanced Non-small-cell Lung Cancer. 2018 Nov 2
15 28455360 Rb Loss and KRAS Mutation Are Predictors of the Response to Platinum-Based Chemotherapy in Pancreatic Neuroendocrine Neoplasm with Grade 3: A Japanese Multicenter Pancreatic NEN-G3 Study. 2017 Aug 15 5
16 29163686 Characterization of distinct types of KRAS mutation and its impact on first-line platinum-based chemotherapy in Chinese patients with advanced non-small cell lung cancer. 2017 Dec 3
17 26740498 Poor response to platinum-based chemotherapy is associated with KRAS mutation and concomitant low expression of BRAC1 and TYMS in NSCLC. 2016 Feb 1
18 26353932 Base excision repair-mediated resistance to cisplatin in KRAS(G12C) mutant NSCLC cells. 2015 Oct 6 1
19 26415993 Comparison of clinical outcome after first-line platinum-based chemotherapy in different types of KRAS mutated advanced non-small-cell lung cancer. 2015 Nov 1
20 26416458 KRAS mutations affect prognosis of non-small-cell lung cancer patients treated with first-line platinum containing chemotherapy. 2015 Oct 20 3
21 26471290 Survival outcome according to KRAS mutation status in newly diagnosed patients with stage IV non-small cell lung cancer treated with platinum doublet chemotherapy. 2015 Oct 6 1
22 24139827 Clinical outcome with platinum-based chemotherapy in patients with advanced nonsquamous EGFR wild-type non-small-cell lung cancer segregated according to KRAS mutation status. 2014 Jan 3
23 24439569 Does KRAS mutational status predict chemoresistance in advanced non-small cell lung cancer (NSCLC)? 2014 Mar 1
24 24768329 Subtype-specific KRAS mutations in advanced lung adenocarcinoma: a retrospective study of patients treated with platinum-based chemotherapy. 2014 Jul 1
25 25081901 A 3'-UTR KRAS-variant is associated with cisplatin resistance in patients with recurrent and/or metastatic head and neck squamous cell carcinoma. 2014 Nov 2
26 23211422 Panitumumab and pegylated liposomal doxorubicin in platinum-resistant epithelial ovarian cancer with KRAS wild-type: the PaLiDo study, a phase II nonrandomized multicenter study. 2013 Jan 1
27 23787801 KRAS mutations in advanced nonsquamous non-small-cell lung cancer patients treated with first-line platinum-based chemotherapy have no predictive value. 2013 Sep 1
28 22139083 A KRAS variant is a biomarker of poor outcome, platinum chemotherapy resistance and a potential target for therapy in ovarian cancer. 2012 Oct 18 2
29 22588152 A pooled exploratory analysis of the effect of tumor size and KRAS mutations on survival benefit from adjuvant platinum-based chemotherapy in node-negative non-small cell lung cancer. 2012 Jun 1
30 21575522 [Relationship between the protein expression of ERCC1, BRCA, β-tubulin and K-ras and the efficacy and prognosis in advanced non-small cell lung cancer]. 2011 Mar 1
31 19281127 [K-ras mutation predictive significance in platinum based chemotherapeutic protocols in patients with advanced non-small cell lung cancer]. 2009 Feb 1