Protein Name glutathione S-transferase pi 1
Organism Homo sapiens
Gene ID 2950
Gene Symbol

GSTP1

UniProt P09211 (GSTP1_HUMAN), V9HWE9 (V9HWE9_HUMAN)
Relationships Total Number of functionally related compound(s) : 703
Total Number of Articles : 964
Description

glutathione S-transferase pi 1

Gene Summary

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]

synonyms
  • glutathione S-transferase P
  • GST class-pi
  • GSTP1-1
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Properties