Platinum

tumor protein p53 ; Homo sapiens







116 Article(s)
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1 34963005 Clonal Hematopoiesis-Associated Gene Mutations in a Clinical Cohort of 448 Patients With Ovarian Cancer. 2022 Apr 11 1
2 35598358 The impact of TP53 co-mutations and immunologic microenvironment on outcome of lung cancer with EGFR exon 20 insertions. 2022 May 19 1
3 32458023 Ubiquitin chromatin remodelling after DNA damage is associated with the expression of key cancer genes and pathways. 2021 Feb 2
4 33183422 Effect of Nano-Platinum on Proliferation and Apoptosis of Non-Small Cell Lung Cancer Cells via P53 Pathway. 2021 Feb 1 1
5 33375991 Characterizing TP53 mutations in ovarian carcinomas with and without concurrent BRCA1 or BRCA2 mutations. 2021 Mar 3
6 33592864 Meta-analysis of P53 expression and sensitivity to platinum-based chemotherapy in patients with non-small cell lung cancer. 2021 Feb 5 4
7 33744756 Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells. 2021 Jun 1
8 33827148 Role of FOXO protein's abnormal activation through PI3K/AKT pathway in platinum resistance of ovarian cancer. 2021 Jun 1
9 34141624 Tumor Genotyping and Homologous Recombination Repair Gene Variants in Patients With Epithelial Ovarian Cancer: Is Pathogenic Enough? 2021 1
10 34298618 Nuclear HKII-P-p53 (Ser15) Interaction is a Prognostic Biomarker for Chemoresponsiveness and Glycolytic Regulation in Epithelial Ovarian Cancer. 2021 Jul 7 1
11 34647981 Preexisting TP53-Variant Clonal Hematopoiesis and Risk of Secondary Myeloid Neoplasms in Patients With High-grade Ovarian Cancer Treated With Rucaparib. 2021 Dec 1 2
12 34794242 The endocytic pathway of Pt nanoclusters and their induced apoptosis of A549 and A549/Cis cells through c-Myc/p53 and Bcl-2/caspase-3 signaling pathways. 2021 Dec 1
13 34967559 Effect of XPD and TP53 Gene Polymorphisms on the Risk of Platinum-Based Chemotherapy Induced Toxicity in Bangladeshi Lung Cancer Patients. 2021 Dec 1 2
14 32344513 Nanoparticle-Mediated Gene Silencing for Sensitization of Lung Cancer to Cisplatin Therapy. 2020 Apr 24 1
15 32382008 The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53. 2020 May 7 1
16 32384200 p53 and MDM2 expression in primary and metastatic testicular germ cell tumors: Association with clinical outcome. 2020 Sep 1
17 32477008 Identification and validation of an individualized autophagy-clinical prognostic index in gastric cancer patients. 2020 1
18 32504383 Influence of Tumor Suppressor p53 Functioning on the Expression of Antioxidant System Genes under the Action of Cytotoxic Compounds. 2020 May 7
19 32611648 A Biomarker-enriched, Randomized Phase II Trial of Adavosertib (AZD1775) Plus Paclitaxel and Carboplatin for Women with Platinum-sensitive TP53-mutant Ovarian Cancer. 2020 Sep 15 1
20 32749686 Phase 2 study of afatinib among patients with recurrent and/or metastatic esophageal squamous cell carcinoma. 2020 Oct 15 1
21 32753889 Sequential Whole Exome Sequencing Reveals Somatic Mutations Associated with Platinum Response in NSCLC. 2020 1
22 32796711 Cellular Responses to Platinum-Based Anticancer Drugs and UVC: Role of p53 and Implications for Cancer Therapy. 2020 Aug 11 1
23 32910383 Association of Molecular Genetic Markers of TP53, MDM2, and CDKN1A Genes with Progression-Free Survival of Patients with Ovarian Cancer after Platinum-Based Chemotherapy. 2020 Aug 1
24 33166854 Genomic characterization of malignant pleural mesothelioma and associated clinical outcomes. 2020 1
25 30301863 Histone Deacetylase Inhibition Has Targeted Clinical Benefit in ARID1A-Mutated Advanced Urothelial Carcinoma. 2019 Jan 1
26 30339780 A redox ruthenium compound directly targets PHD2 and inhibits the HIF1 pathway to reduce tumor angiogenesis independently of p53. 2019 Jan 1
27 30538112 Identification and Characterization of Synthetic Viability with ERCC1 Deficiency in Response to Interstrand Crosslinks in Lung Cancer. 2019 Apr 15 3
28 30896089 New insights into germ cell tumor genomics. 2019 Jul 1
29 31295913 Platinum Salts in Patients with Breast Cancer: A Focus on Predictive Factors. 2019 Jul 10 1
30 31581548 Clonal Evolution of TP53 c.375+1G>A Mutation in Pre- and Post- Neo-Adjuvant Chemotherapy (NACT) Tumor Samples in High-Grade Serous Ovarian Cancer (HGSOC). 2019 Oct 1 1
31 31798724 Cisplatin effect on head and neck squamous cell carcinoma cells is modulated by ERK1/2 protein kinases. 2019 Dec 5
32 31877751 Identification and Characterization of a New Platinum-Induced TP53 Mutation in MDAH Ovarian Cancer Cells. 2019 Dec 21 5
33 29301826 p53-Reactive T Cells Are Associated with Clinical Benefit in Patients with Platinum-Resistant Epithelial Ovarian Cancer After Treatment with a p53 Vaccine and Gemcitabine Chemotherapy. 2018 Mar 15 2
34 29307819 Absence of REV3L promotes p53-regulated cancer cell metabolism in cisplatin-treated lung carcinoma cells. 2018 Jan 29 1
35 29690507 Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress. 2018 Apr 21 1
36 29783665 Identification of Novel Somatic TP53 Mutations in Patients with High-Grade Serous Ovarian Cancer (HGSOC) Using Next-Generation Sequencing (NGS). 2018 May 18 1
37 30106452 Integrin β4 reduces DNA damage‑induced p53 activation in colorectal cancer. 2018 Oct 6
38 30205260 Novel tacrine platinum(II) complexes display high anticancer activity via inhibition of telomerase activity, dysfunction of mitochondria, and activation of the p53 signaling pathway. 2018 Oct 5 1
39 30375398 The cisplatin-induced lncRNA PANDAR dictates the chemoresistance of ovarian cancer via regulating SFRS2-mediated p53 phosphorylation. 2018 Oct 30 1
40 28031409 Functional Activation of Mutant p53 by Platinum Analogues in Cisplatin-Resistant Cells Is Dependent on Phosphorylation. 2017 Mar 3
41 28494179 Predictive biomarkers for triple negative breast cancer treated with platinum-based chemotherapy. 2017 Jun 3 1
42 28730758 Platinum derivatives: a multidisciplinary approach. 2017 May-Jun 1
43 27191893 Paclitaxel is necessary for improved survival in epithelial ovarian cancers with homologous recombination gene mutations. 2016 Jul 26 2
44 27313779 P53 Is Involved in a Three-Dimensional Architecture-Mediated Decrease in Chemosensitivity in Colon Cancer. 2016 3
45 27614750 Association of p53 codon 72 polymorphism and survival of North Indian lung cancer patients treated with platinum-based chemotherapy. 2016 Dec 1
46 27998224 Phase II Study of WEE1 Inhibitor AZD1775 Plus Carboplatin in Patients With TP53-Mutated Ovarian Cancer Refractory or Resistant to First-Line Therapy Within 3 Months. 2016 Dec 20 2
47 25263447 p53 protein aggregation promotes platinum resistance in ovarian cancer. 2015 Jul 1
48 25385265 TP53 oncomorphic mutations predict resistance to platinum‑ and taxane‑based standard chemotherapy in patients diagnosed with advanced serous ovarian carcinoma. 2015 Feb 2
49 25407898 Nucleolar targeting by platinum: p53-independent apoptosis follows rRNA inhibition, cell-cycle arrest, and DNA compaction. 2015 Jan 5 1
50 25691460 Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients. 2015 Apr 1 1