Platinum

erb-b2 receptor tyrosine kinase 2 ; Homo sapiens







50 Article(s)
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1 34420059 Prognostic value of natural killer cell activity for patients with HER2 + advanced gastric cancer treated with first-line fluoropyrimidine-platinum doublet plus trastuzumab. 2022 Apr 2
2 34933901 Early Tumor-Immune Microenvironmental Remodeling and Response to First-Line Fluoropyrimidine and Platinum Chemotherapy in Advanced Gastric Cancer. 2022 Apr 1 2
3 35092538 Examining the prevalence of homologous recombination repair defects in ER+ breast cancers. 2022 Apr 1
4 32970266 External validity of docetaxel triplet trials in advanced gastric cancer: are there patients who still benefit? 2021 Mar 1
5 33569679 Sensitive sandwich-type voltammetric immunosensor for breast cancer biomarker HER2 detection based on gold nanoparticles decorated Cu-MOF and Cu2ZnSnS4 NPs/Pt/g-C3N4 composite. 2021 Feb 10 1
6 33916671 Au@Pt Core-Shell Nanoparticle Bioconjugates for the Therapy of HER2+ Breast Cancer and Hepatocellular Carcinoma. Model Studies on the Applicability of 193mPt and 195mPt Radionuclides in Auger Electron Therapy. 2021 Apr 3 1
7 33932503 Adjuvant T-DM1 versus trastuzumab in patients with residual invasive disease after neoadjuvant therapy for HER2-positive breast cancer: subgroup analyses from KATHERINE. 2021 Aug 1
8 34293698 Platinum complexes inhibit HER-2 enriched and triple-negative breast cancer cells metabolism to suppress growth, stemness and migration by targeting PKM/LDHA and CCND1/BCL2/ATG3 signaling pathways. 2021 Nov 15 1
9 31815582 Randomized, Phase II Study Prospectively Evaluating Treatment of Metastatic Esophageal, Gastric, or Gastroesophageal Cancer by Gene Expression of ERCC1: SWOG S1201. 2020 Feb 10 1
10 32235305 Local and Central Evaluation of HER2 Positivity and Clinical Outcome in Advanced Gastric and Gastroesophageal Cancer-Results from the AGMT GASTRIC-5 Registry. 2020 Mar 29 1
11 32735623 Second-line treatment in advanced gastric cancer: Data from the Spanish AGAMENON registry. 2020 1
12 32750194 A Multi-action PtIV Conjugate with Oleate and Cinnamate Ligands Targets Human Epithelial Growth Factor Receptor HER2 in Aggressive Breast Cancer Cells. 2020 Nov 16 1
13 32984690 Red-Fluorescent Pt Nanoclusters for Detecting and Imaging HER2 in Breast Cancer Cells. 2020 Sep 22 2
14 30124494 Phase II clinical trial of second-line weekly paclitaxel plus trastuzumab for patients with HER2-positive metastatic gastric cancer. 2019 Jan 2
15 30504425 NRF2 through RPS6 Activation Is Related to Anti-HER2 Drug Resistance in HER2-Amplified Gastric Cancer. 2019 Mar 1 1
16 30909992 [Association between the HER2 Gene Status and the Efficacy of First-line Pemetrexed Combined with Platinum Chemotherapy in Patients with Advanced Lung 
Adenocarcinoma]. 2019 Mar 20 4
17 31409079 Effectiveness of Neoadjuvant Therapy with Platinum-Based Agents for Patients with BRCA1 and BRCA2 Germline Mutations - A Retrospective Analysis of Breast Cancer Patients Treated at MMCI Brno. 2019 Summer 1
18 30326862 Predictive impact of absolute lymphocyte counts for progression-free survival in human epidermal growth factor receptor 2-positive advanced breast cancer treated with pertuzumab and trastuzumab plus eribulin or nab-paclitaxel. 2018 Oct 16 1
19 28944120 Treatment of Male Breast Cancer by Dual Human Epidermal Growth Factor Receptor 2 (HER2) Blockade and Response Prediction Using Novel Optical Tomography Imaging: A Case Report. 2017 Jul 17 1
20 28989055 Down-regulation of HECTD3 by HER2 inhibition makes serous ovarian cancer cells sensitive to platinum treatment. 2017 Dec 28 1
21 29254172 Trastuzumab beyond progression in patients with HER2-positive advanced gastric adenocarcinoma: a multicenter AGEO study. 2017 Nov 24 1
22 26588239 Evaluation of TOP2A as a Predictive Marker for Endometrial Cancer With Taxane-Containing Adjuvant Chemotherapy. 2016 Feb 1
23 26693899 Genetic heterogeneity after first-line chemotherapy in high-grade serous ovarian cancer. 2016 Jan 2
24 27016235 Germline mutations of the DNA repair pathways in uterine serous carcinoma. 2016 Apr 1
25 27044931 Afatinib Activity in Platinum-Refractory Metastatic Urothelial Carcinoma in Patients With ERBB Alterations. 2016 Jun 20 1
26 25467313 Pathologic complete response rates in triple-negative, HER2-positive, and hormone receptor-positive breast cancers after anthracycline-free neoadjuvant chemotherapy with carboplatin and paclitaxel with or without trastuzumab. 2015 Feb 2
27 25602630 PRP4K is a HER2-regulated modifier of taxane sensitivity. 2015 1
28 26099969 Phase II study of trastuzumab in combination with S-1 and cisplatin in the first-line treatment of human epidermal growth factor receptor HER2-positive advanced gastric cancer. 2015 Aug 1
29 26186063 Trastuzumab-mediated selective delivery for platinum drug to HER2-positive breast cancer cells. 2015 Oct 1
30 26211591 Biological evaluation of a novel Herceptin-platinum (II) conjugate for efficient and cancer cell specific delivery. 2015 Jul 2
31 26359224 Advancing pharmacological treatment options for advanced gastric cancer. 2015 1
32 23680713 Esophageal carcinoma: are modern targeted therapies shaking the rock? 2013 Jul 1
33 22396490 Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors. 2012 May 1 1
34 22990650 Individuality in FGF1 expression significantly influences platinum resistance and progression-free survival in ovarian cancer. 2012 Oct 9 1
35 23197882 Advanced gastric cancer: is there enough evidence to call second-line therapy standard? 2012 Nov 28 1
36 21135055 An aCGH classifier derived from BRCA1-mutated breast cancer and benefit of high-dose platinum-based chemotherapy in HER2-negative breast cancer patients. 2011 Jul 1
37 21985855 Successful treatment of a patient with HER2-positive metastatic gastric cancer with third-line combination therapy with irinotecan, 5-fluorouracil, leucovorin and trastuzumab (FOLFIRI-T). 2011 1
38 20417484 Differential sensitivity to platinum-based chemotherapy in primary uterine serous papillary carcinoma cell lines with high vs low HER-2/neu expression in vitro. 2010 Aug 6
39 19258951 Prognostic value of human epidermal growth factor receptor 2 (Her-2)/neu in patients with advanced ovarian cancer treated with platinum/paclitaxel as first-line chemotherapy: a retrospective evaluation of the AGO-OVAR 3 Trial by the AGO OVAR Germany. 2009 Jan 4
40 19028616 The Renaissance of platinum-based chemotherapy for metastatic breast cancer. 2008 Oct 1
41 15865102 Tissue expression and serum levels of the oncoprotein HER-2/neu in 157 primary breast tumours. 2005 Mar-Apr 1
42 14729645 Molecular determinants of the cytotoxicity of platinum compounds: the contribution of in silico research. 2004 Jan 1 2
43 15545967 TP53 status determines clinical significance of ERBB2 expression in ovarian cancer. 2004 Nov 29 1
44 15685824 Gemcitabine in combination with trastuzumab and/or platinum salts in breast cancer cells with HER2 overexpression. 2004 Dec 1
45 19780241 Breast cancer: review of platinum-based cooperative group trials. 2004 Sep 1
46 12694661 Her-2/neu expression in ovarian cancer: pre- and postexposure to platinum chemotherapy. 2003 Apr 3
47 11899413 Platinum compounds in the treatment of advanced breast cancer. 2001 Oct 6
48 9475194 Overexpression of the oncogene c-erbB-2 (HER2/neu) and response to chemotherapy in patients with ovarian cancer. 1998 Jan 1
49 9383735 Antioxidants for prevention of methionine oxidation in recombinant monoclonal antibody HER2. 1997 Nov 1
50 8652251 An I.T.M.O. group study on second-line treatment in advanced epithelial ovarian cancer: an attempt to identify clinical and biological factors determining prognosis. 1995 Dec 1