| Protein Name | DNA polymerase iota |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 11201 |
| Gene Symbol | POLI |
| UniProt | Q9UNA4 (POLI_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
1165
Total Number of Articles : 709 |
Description |
DNA polymerase iota |
| Gene Summary |
The protein encoded by this gene is an error-prone DNA polymerase involved in DNA repair. The encoded protein promotes DNA synthesis across lesions in the template DNA, which other polymerases cannot do. The encoded polymerase inserts deoxynucleotides across lesions and then relies on DNA polymerase zeta to extend the nascent DNA strand to bypass the lesion. [provided by RefSeq, May 2017] |
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| Properties | |