Protein Name | ERCC excision repair 4, endonuclease catalytic subunit |
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Organism | Homo sapiens |
Gene ID | 2072 |
Gene Symbol | ERCC4 |
UniProt | Q92889 (XPF_HUMAN), A0A1W1GSK9 (A0A1W1GSK9_HUMAN), B4DXD8 (B4DXD8_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
87
Total Number of Articles : 115 |
Description |
ERCC excision repair 4, endonuclease catalytic subunit |
Gene Summary |
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009] |
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