Platinum

poly(ADP-ribose) polymerase 1 ; Homo sapiens







125 Article(s)
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1 33926263 Effect of PARP Inhibitors as Maintenance Treatment on Restricted Mean Survival Time in Platinum-Sensitive Recurrent Ovarian Cancer: A Systematic Review and Meta-analysis. 2022 Jan 3
2 35018214 Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models. 2022 1
3 35124372 TOPBP1 regulates resistance of gastric cancer to oxaliplatin by promoting transcription of PARP1. 2022 Mar 5
4 35219776 The impact of olaparib dose reduction and treatment interruption on treatment outcome in the SOLO2/ENGOT-ov21 platinum-sensitive recurrent ovarian cancer. 2022 Jun 2
5 35396812 A phase I study of talazoparib (BMN 673) combined with carboplatin and paclitaxel in patients with advanced solid tumors (NCI9782). 2022 Apr 8 2
6 33250205 Olaparib maintenance therapy in patients with newly diagnosed advanced ovarian cancer and a BRCA1 and/or BRCA2 mutation: SOLO1 China cohort. 2021 Jan 1
7 33423551 Oregovomab: an investigational agent for the treatment of advanced ovarian cancer. 2021 Feb 2
8 33478135 The Prognostic Relevance of Poly (ADP-Ribose) Polymerase Expression in Ovarian Cancer Tissue of Wild Type and BRCA-Mutation Carrier Patients. 2021 Jan 19 2
9 33515422 SEOM clinical guideline in ovarian cancer (2020). 2021 May 1
10 33617901 Patient-derived xenograft models of BRCA-associated pancreatic cancers. 2021 Apr 1
11 33669671 Effect of Oxaliplatin, Olaparib and LY294002 in Combination on Triple-Negative Breast Cancer Cells. 2021 Feb 19 1
12 33675937 The systemic treatment of recurrent ovarian cancer revisited. 2021 Jun 2
13 33724122 Poly (ADP-ribose) polymerase (PARP) as target for the treatment of epithelial ovarian cancer: what to know. 2021 May 1
14 33740262 Molecular and clinical predictors of improvement in progression-free survival with maintenance PARP inhibitor therapy in women with platinum-sensitive, recurrent ovarian cancer: A meta-analysis. 2021 Jul 15 1
15 33743851 Olaparib tablets as maintenance therapy in patients with platinum-sensitive relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a final analysis of a double-blind, randomised, placebo-controlled, phase 3 trial. 2021 May 1
16 33882241 PARP inhibitors and immunotherapy in ovarian and endometrial cancers. 2021 Dec 1
17 33920140 Combination of Niraparib, Cisplatin and Twist Knockdown in Cisplatin-Resistant Ovarian Cancer Cells Potentially Enhances Synthetic Lethality through ER-Stress Mediated Mitochondrial Apoptosis Pathway. 2021 Apr 10 1
18 34132814 Association of T2285C polymorphism in PARP1 gene coding region with its expression, activity and NSCLC risk along with prognosis. 2021 Aug 27 1
19 34520432 PARP inhibitors decrease response to subsequent platinum-based chemotherapy in patients with BRCA mutated ovarian cancer. 2021 Nov 1 1
20 34593416 Treatment of Metastatic Castration-resistant Prostate Cancer: Are PARP Inhibitors Shifting the Paradigm? 2021 Oct 2
21 34616492 Population-adjusted indirect treatment comparison of maintenance PARP inhibitor with or without bevacizumab versus bevacizumab alone in women with newly diagnosed advanced ovarian cancer. 2021 2
22 34900739 Comparison of the Efficacy and Safety of PARP Inhibitors as a Monotherapy for Platinum-Sensitive Recurrent Ovarian Cancer: A Network Meta-Analysis. 2021 1
23 34948122 New Synthetic Lethality Re-Sensitizing Platinum-Refractory Cancer Cells to Cisplatin In Vitro: The Rationale to Co-Use PARP and ATM Inhibitors. 2021 Dec 11 1
24 34955157 Mise à jour 2021 des recommandations pour la pratique clinique de Nice/Saint-Paul-de-Vence dans le cancer de l’ovaire épithélial de haut grade: Updated 2021 recommendations for the clinical practice of Nice/Saint-Paul-de-Vence in epithelial high grade ovarian cancer. 2021 Dec 1
25 31534014 ALDH1A1 Contributes to PARP Inhibitor Resistance via Enhancing DNA Repair in BRCA2-/- Ovarian Cancer Cells. 2020 Jan 4
26 31553293 Advances in the Treatment of Ovarian Cancer Using PARP Inhibitors and the Underlying Mechanism of Resistance. 2020 1
27 31594824 ADP-Ribosylation Levels and Patterns Correlate with Gene Expression and Clinical Outcomes in Ovarian Cancers. 2020 Jan 1
28 31650446 Veliparib in ovarian cancer: a new synthetically lethal therapeutic approach. 2020 Feb 1
29 31669203 PARP1 blockade is synthetically lethal in XRCC1 deficient sporadic epithelial ovarian cancers. 2020 Jan 28 1
30 31721706 Anticancer Activity of Platinum (II) Complex with 2-Benzoylpyridine by Induction of DNA Damage, S-Phase Arrest, and Apoptosis. 2020 3
31 31856090 ATM-Mutated Pancreatic Cancer: Clinical and Molecular Response to Gemcitabine/Nab-Paclitaxel After Genome-Based Therapy Resistance. 2020 Jan 1
32 31863638 Biguanides in combination with olaparib limits tumorigenesis of drug-resistant ovarian cancer cells through inhibition of Snail. 2020 Feb 1
33 31902551 Association of expression of p53, livin, ERCC1, BRCA1 and PARP1 in epithelial ovarian cancer tissue with drug resistance and prognosis. 2020 Feb 1
34 32171277 Polyclonal BRCA2 mutations following carboplatin treatment confer resistance to the PARP inhibitor rucaparib in a patient with mCRPC: a case report. 2020 Mar 14 1
35 32172572 Niraparib for the Treatment of Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer. 2020 Oct 2
36 32186787 [PARP INHIBITORS FOR ADJUVANT TREATMENT FOR OVARIAN CANCER]. 2020 Mar 2
37 32321768 Real world outcomes in platinum sensitive relapsed ovarian, fallopian tube, or peritoneal cancer treated in routine clinical practice in the United Kingdom prior to poly-ADP ribose polymerase inhibitors. 2020 Jul 2
38 32471249 PARP Inhibitors in the Treatment of Early Breast Cancer: The Step Beyond? 2020 May 27 1
39 32471250 Bevacizumab or PARP-Inhibitors Maintenance Therapy for Platinum-Sensitive Recurrent Ovarian Cancer: A Network Meta-Analysis. 2020 May 27 1
40 32512040 The DNA damage response pathway as a land of therapeutic opportunities for colorectal cancer. 2020 Sep 1
41 32569725 The forefront of ovarian cancer therapy: update on PARP inhibitors. 2020 Sep 2
42 32575908 Drugs Targeting Tumor-Initiating Cells Prolong Survival in a Post-Surgery, Post-Chemotherapy Ovarian Cancer Relapse Model. 2020 Jun 21 1
43 32594311 The Prognostic Value of PARP Expression in High-Grade Epithelial Ovarian Cancer. 2020 Oct 1
44 32601814 Targeting DNA Damage Repair Pathways in Pancreatic Adenocarcinoma. 2020 Jun 29 1
45 32609666 The role of PARP inhibitors in germline BRCA-associated pancreatic ductal adenocarcinoma. 2020 Mar 1
46 32612955 Efficacy and Prognostic Factors for PARP Inhibitors in Patients With Ovarian Cancer. 2020 1
47 32793315 Retrospective review of outcomes in patients with DNA-damage repair related pancreatic cancer. 2020 1
48 32817083 Poly (ADP-ribose) polymerase (PARP) inhibitor regimens for ovarian cancer in phase III randomized controlled trials: a network meta-analysis. 2020 Oct 4
49 32878963 DUETTE: a phase II randomized, multicenter study to investigate the efficacy and tolerability of a second maintenance treatment in patients with platinum-sensitive relapsed epithelial ovarian cancer, who have previously received poly(ADP-ribose) polymerase (PARP) inhibitor maintenance treatment. 2020 Nov 3
50 32953627 Secondary and tertiary ovarian cancer recurrence: what is the best management? 2020 Aug 2