Protein Name hydroxyacid oxidase 1
Organism Homo sapiens
Gene ID 54363
Gene Symbol


UniProt Q9UJM8 (HAOX1_HUMAN), A8K058 (A8K058_HUMAN)
Relationships Total Number of functionally related compound(s) : 931
Total Number of Articles : 1167

hydroxyacid oxidase 1

Gene Summary

This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008]

  • 2-Hydroxyacid oxidase 1
  • (S)-2-hydroxy-acid oxidase
  • glycolate oxidase 1
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