Platinum

ATP binding cassette subfamily C member 2 ; Homo sapiens







20 Article(s)
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1 34347217 Association between ABCC2 polymorphism and hematological toxicity in patients with esophageal cancer receiving platinum plus 5-fluorouracil therapy. 2022 Jan 4
2 29660381 ARID1A ablation leads to multiple drug resistance in ovarian cancer via transcriptional activation of MRP2. 2018 Jul 28 1
3 28442702 Effect of GSTP1 and ABCC2 Polymorphisms on Treatment Response in Patients with Advanced Non-Small Cell Lung Cancer Undergoing Platinum-Based Chemotherapy: A Study in a Chinese Uygur Population. 2017 Apr 26 1
4 28982859 Changes in the Expression of Various Transporters as Influencing Factors of Resistance to Cisplatin. 2017 Oct 1
5 26816351 ABCC2 polymorphisms and survival in the Princess Margaret cohort study and the NCIC clinical trials group BR.24 trial of platinum-treated advanced stage non-small cell lung cancer patients. 2016 Apr 5
6 27014726 Data showing the circumvention of oxaliplatin resistance by vatalanib in colon cancer. 2016 Jun 2
7 27487151 ABCC2-24C > T polymorphism is associated with the response to platinum/5-Fu-based neoadjuvant chemotherapy and better clinical outcomes in advanced gastric cancer patients. 2016 Aug 23 1
8 27590272 Associations of genetic polymorphisms of the transporters organic cation transporter 2 (OCT2), multidrug and toxin extrusion 1 (MATE1), and ATP-binding cassette subfamily C member 2 (ABCC2) with platinum-based chemotherapy response and toxicity in non-small cell lung cancer patients. 2016 Sep 2 5
9 27748801 Acquisition of anticancer drug resistance is partially associated with cancer stemness in human colon cancer cells. 2016 Dec 1
10 26131551 Multidrug Resistance-Associated Protein 2 (MRP2) Mediated Transport of Oxaliplatin-Derived Platinum in Membrane Vesicles. 2015 7
11 24641901 Transgenic expression of the human MRP2 transporter reduces cisplatin accumulation and nephrotoxicity in Mrp2-null mice. 2014 May 2
12 20943283 Association of ABCC2 polymorphisms with platinum-based chemotherapy response and severe toxicity in non-small cell lung cancer patients. 2011 May 2
13 21687948 'Genetic profiling' and ovarian cancer therapy (review). 2011 Sep-Oct 1
14 19568750 MRP2 and GSTP1 polymorphisms and chemotherapy response in advanced non-small cell lung cancer. 2010 Feb 4
15 18214043 Immunohistochemical expression of MRP2 and clinical resistance to platinum-based chemotherapy in small cell lung cancer. 2007 Nov-Dec 4
16 16213010 MRP2 (ABCC2) and cisplatin sensitivity in hepatocytes and human ovarian carcinoma. 2006 Feb 4
17 17145840 ABCC2 (MRP2, cMOAT) can be localized in the nuclear membrane of ovarian carcinomas and correlates with resistance to cisplatin and clinical outcome. 2006 Dec 1 1
18 15688364 Protection of platinum-DNA adduct formation and reversal of cisplatin resistance by anti-MRP2 hammerhead ribozymes in human cancer cells. 2005 Jun 20 5
19 12839578 Overexpression of cMOAT (MRP2/ABCC2) is associated with decreased formation of platinum-DNA adducts and decreased G2-arrest in melanoma cells resistant to cisplatin. 2003 Jul 9
20 11332988 Kinetic characterization of ribozymes directed against the cisplatin resistance-associated ABC transporter cMOAT/MRP2/ABCC2. 2001 Mar 3