Cucurbitacins


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60 Functionally related protein(s)
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Protein Name
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UniProt Entry
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Gene Symbol
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Organism
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NCBI Gene ID
# All related compound(s)
#Article(s)
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1 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 11
2 cofilin 1 COF1_HUMAN CFL1 Homo sapiens 1072 348 4
3 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 4
4 signal transducer and activator of transcription 3 STAT3_MOUSE Stat3 Mus musculus 20848 1288 4
5 prostaglandin-endoperoxide synthase 2 PGH2_HUMAN PTGS2 Homo sapiens 5743 2572 3
6 mitochondrially encoded cytochrome c oxidase II COX2_HUMAN COX2 Homo sapiens 4513 5330 2
7 signal transducer and activator of transcription 3 STAT3_RAT Stat3 Rattus norvegicus 25125 689 2
8 TNF superfamily member 10 TNF10_HUMAN TNFSF10 Homo sapiens 8743 1439 2
9 epidermal growth factor receptor EGFR_HUMAN EGFR Homo sapiens 1956 4580 2
10 Janus kinase 2 JAK2_MOUSE Jak2 Mus musculus 16452 466 2
11 microtubule associated protein 1 light chain 3 alpha MLP3A_HUMAN MAP1LC3A Homo sapiens 84557 710 2
12 tyrosinase TYRO_MOUSE Tyr Mus musculus 22173 808 1
13 KRAS proto-oncogene, GTPase RASK_HUMAN KRAS Homo sapiens 3845 1547 1
14 homeobox C10 HXC10_HUMAN HOXC10 Homo sapiens 3226 819 1
15 cytokine like 1 CYTL1_HUMAN CYTL1 Homo sapiens 54360 453 1
16 X-linked Kx blood group XK_HUMAN XK Homo sapiens 7504 753 1
17 polymerase (RNA) III (DNA directed) polypeptide K RPC10_MOUSE Polr3k Mus musculus 67005 63 1
18 GLI family zinc finger 1 GLI1_HUMAN GLI1 Homo sapiens 2735 334 1
19 tumor protein p53 P53_HUMAN TP53 Homo sapiens 7157 5584 1
20 neurotrophic receptor tyrosine kinase 1 NTRK1_RAT Ntrk1 Rattus norvegicus 59109 312 1
21 mitogen-activated protein kinase 14 MK14_HUMAN MAPK14 Homo sapiens 1432 3132 1
22 ATPase, class II, type 9A ATP9A_MOUSE Atp9a Mus musculus 11981 227 1
23 ATM serine/threonine kinase ATM_HUMAN ATM Homo sapiens 472 847 1
24 heme oxygenase 1 HMOX1_HUMAN HMOX1 Homo sapiens 3162 1764 1
25 cingulin D4A4X4_RAT Cgn Rattus norvegicus 310655 21 1
26 caspase 8 CASP8_HUMAN CASP8 Homo sapiens 841 1641 1
27 mitochondrially encoded cytochrome c oxidase I COX1_HUMAN COX1 Homo sapiens 4512 1134 1
28 prostaglandin-endoperoxide synthase 1 PGH1_HUMAN PTGS1 Homo sapiens 5742 531 1
29 catenin beta 1 CTNB1_HUMAN CTNNB1 Homo sapiens 1499 2350 1
30 ribosomal protein S18 RS18_HUMAN RPS18 Homo sapiens 6222 15 1
31 mitogen-activated protein kinase 8 MK08_HUMAN MAPK8 Homo sapiens 5599 2863 1
32 surface glycoprotein SPIKE_SARS2 SPIKE_SARS2 Severe acute respiratory syndrome coronavirus 2 43740568 640 1
33 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 1
34 CREB regulated transcription coactivator 1 CRTC1_MOUSE Crtc1 Mus musculus 382056 993 1
35 ribosomal protein S6 kinase B1 KS6B1_HUMAN RPS6KB1 Homo sapiens 6198 764 1
36 AKT serine/threonine kinase 1 AKT1_RAT Akt1 Rattus norvegicus 24185 2385 1
37 NFE2 like bZIP transcription factor 2 NF2L2_HUMAN NFE2L2 Homo sapiens 4780 2545 1
38 toll like receptor 2 TLR2_HUMAN TLR2 Homo sapiens 7097 778 1
39 Janus kinase 2 JAK2_RAT Jak2 Rattus norvegicus 24514 336 1
40 B-Raf proto-oncogene, serine/threonine kinase BRAF_HUMAN BRAF Homo sapiens 673 872 1
41 nitric oxide synthase 2 NOS2_HUMAN NOS2 Homo sapiens 4843 2012 1
42 anoctamin 1, calcium activated chloride channel ANO1_MOUSE Ano1 Mus musculus 101772 129 1
43 TNF receptor superfamily member 11b TR11B_HUMAN TNFRSF11B Homo sapiens 4982 502 1
44 RUNX family transcription factor 2 RUNX2_HUMAN RUNX2 Homo sapiens 860 661 1
45 sonic hedgehog signaling molecule SHH_HUMAN SHH Homo sapiens 6469 354 1
46 signal transducer and activator of transcription 3 E2RB82_CANLF STAT3 Canis lupus familiaris 490967 15 1
47 Ecdysone receptor ECR_DROME EcR Drosophila melanogaster 35540 49 1
48 Janus kinase 2 E2RPW6_CANLF JAK2 Canis lupus familiaris 484185 2 1
49 cytochrome P450 CYP72A219 - CYP Cucumis sativus 101213974 1 1
50 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 1