| Protein Name | neurotrophic receptor tyrosine kinase 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 59109 |
| Gene Symbol | Ntrk1 |
| UniProt | P35739 (NTRK1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
312
Total Number of Articles : 428 |
Description |
neurotrophic receptor tyrosine kinase 1 |
| Gene Summary |
Enables several functions, including GPI-linked ephrin receptor activity; nerve growth factor binding activity; and neurotrophin p75 receptor binding activity. Involved in several processes, including detection of stimulus involved in sensory perception of pain; nervous system development; and positive regulation of cell communication. Acts upstream of or within cellular response to growth factor stimulus and protein autophosphorylation. Located in several cellular components, including cell surface; endosome; and neuronal cell body. Part of protein-containing complex. Used to study Parkinsonism; glaucoma; and myofascial pain syndrome. Biomarker of several diseases, including colitis; diabetic neuropathy; glaucoma; periodontitis; and retinal detachment. Human ortholog(s) of this gene implicated in Alzheimer's disease; hereditary sensory neuropathy; hereditary sensory neuropathy type 4; and schizophrenia. Orthologous to human NTRK1 (neurotrophic receptor tyrosine kinase 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |