ponatinib


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215 Functionally related protein(s)
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Protein Name
UniProt Entry
Gene Symbol
Organism
NCBI Gene ID
# All related compound(s)
#Article(s)
1 ABL proto-oncogene 1, non-receptor tyrosine kinase ABL1_HUMAN ABL1 Homo sapiens 25 989 98
2 BCR activator of RhoGEF and GTPase BCR_HUMAN BCR Homo sapiens 613 263 28
3 fibroblast growth factor receptor 1 FGFR1_HUMAN FGFR1 Homo sapiens 2260 405 20
4 KIT proto-oncogene, receptor tyrosine kinase KIT_HUMAN KIT Homo sapiens 3815 679 11
5 SRC proto-oncogene, non-receptor tyrosine kinase SRC_HUMAN SRC Homo sapiens 6714 2142 10
6 fibroblast growth factor receptor 4 FGFR4_HUMAN FGFR4 Homo sapiens 2264 174 9
7 ret proto-oncogene RET_HUMAN RET Homo sapiens 5979 674 9
8 fibroblast growth factor receptor 2 FGFR2_HUMAN FGFR2 Homo sapiens 2263 228 8
9 mechanistic target of rapamycin kinase MTOR_HUMAN MTOR Homo sapiens 2475 3411 8
10 fms related receptor tyrosine kinase 3 FLT3_HUMAN FLT3 Homo sapiens 2322 569 7
11 c-abl oncogene 1, non-receptor tyrosine kinase ABL1_MOUSE Abl1 Mus musculus 11350 160 7
12 AKT serine/threonine kinase 1 AKT1_HUMAN AKT1 Homo sapiens 207 6445 7
13 BCR activator of RhoGEF and GTPase BCR_MOUSE Bcr Mus musculus 110279 102 7
14 fibroblast growth factor receptor 1 FGFR1_MOUSE Fgfr1 Mus musculus 14182 127 6
15 CD34 molecule CD34_HUMAN CD34 Homo sapiens 947 1218 6
16 platelet derived growth factor receptor alpha PGFRA_HUMAN PDGFRA Homo sapiens 5156 229 6
17 mitogen-activated protein kinase 3 MK03_HUMAN MAPK3 Homo sapiens 5595 3238 5
18 kinase insert domain receptor VGFR2_HUMAN KDR Homo sapiens 3791 1635 5
19 fibroblast growth factor 2 FGF2_HUMAN FGF2 Homo sapiens 2247 1502 5
20 signal transducer and activator of transcription 5A STA5A_HUMAN STAT5A Homo sapiens 6776 575 5
21 ATP binding cassette subfamily B member 1 MDR1_HUMAN ABCB1 Homo sapiens 5243 3985 4
22 factor interacting with PAPOLA and CPSF1 FIP1_HUMAN FIP1L1 Homo sapiens 81608 167 4
23 signal transducer and activator of transcription 3 STAT3_HUMAN STAT3 Homo sapiens 6774 2503 4
24 LYN proto-oncogene, Src family tyrosine kinase LYN_HUMAN LYN Homo sapiens 4067 285 4
25 signal transducer and activator of transcription 5A STA5A_MOUSE Stat5a Mus musculus 20850 224 3
26 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_HUMAN ABCG2 Homo sapiens 9429 1370 3
27 MYC proto-oncogene, bHLH transcription factor MYC_HUMAN MYC Homo sapiens 4609 2261 3
28 MCL1 apoptosis regulator, BCL2 family member MCL1_HUMAN MCL1 Homo sapiens 4170 1015 3
29 tumor necrosis factor TNFA_HUMAN TNF Homo sapiens 7124 8006 3
30 platelet derived growth factor receptor beta PGFRB_HUMAN PDGFRB Homo sapiens 5159 417 3
31 caspase 3 CASP3_HUMAN CASP3 Homo sapiens 836 5209 3
32 ATP binding cassette subfamily G member 2 (Junior blood group) ABCG2_MOUSE Abcg2 Mus musculus 26357 461 2
33 receptor interacting serine/threonine kinase 3 RIPK3_HUMAN RIPK3 Homo sapiens 11035 184 2
34 vascular endothelial growth factor A VEGFA_HUMAN VEGFA Homo sapiens 7422 4023 2
35 fms related receptor tyrosine kinase 1 VGFR1_HUMAN FLT1 Homo sapiens 2321 547 2
36 mitogen-activated protein kinase kinase 7 MP2K7_HUMAN MAP2K7 Homo sapiens 5609 1407 2
37 AXL receptor tyrosine kinase UFO_HUMAN AXL Homo sapiens 558 302 2
38 cyclin D1 CCND1_HUMAN CCND1 Homo sapiens 595 1747 2
39 phosphoglycolate phosphatase PGP_MOUSE Pgp Mus musculus 67078 756 2
40 receptor interacting serine/threonine kinase 2 RIPK2_HUMAN RIPK2 Homo sapiens 8767 90 2
41 receptor interacting serine/threonine kinase 1 RIPK1_HUMAN RIPK1 Homo sapiens 8737 356 2
42 KIT proto-oncogene receptor tyrosine kinase KIT_MOUSE Kit Mus musculus 16590 294 2
43 cytochrome P450 family 3 subfamily A member 4 CP3A4_HUMAN CYP3A4 Homo sapiens 1576 3475 2
44 mitogen-activated protein kinase 1 MK01_HUMAN MAPK1 Homo sapiens 5594 4181 2
45 phenylalanine hydroxylase PH4H_HUMAN PAH Homo sapiens 5053 991 2
46 fibroblast growth factor receptor 2 FGFR2_MOUSE Fgfr2 Mus musculus 14183 70 2
47 LCK proto-oncogene, Src family tyrosine kinase LCK_HUMAN LCK Homo sapiens 3932 378 2
48 interferon gamma IFNG_HUMAN IFNG Homo sapiens 3458 3371 2
49 interleukin 6 IL6_HUMAN IL6 Homo sapiens 3569 5444 2
50 C-X-C motif chemokine ligand 8 IL8_HUMAN CXCL8 Homo sapiens 3576 4038 1