CPRiL

Protein Name	receptor interacting serine/threonine kinase 2
Organism	Homo sapiens
Gene ID	8767
Gene Symbol	RIPK2
UniProt	O43353 (RIPK2_HUMAN), A0A0S2Z4Z8 (A0A0S2Z4Z8_HUMAN)
Relationships	Total Number of functionally related compound(s) : 90 Total Number of Articles : 89
Description	receptor interacting serine/threonine kinase 2
Gene Summary	This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008]
synonyms	receptor-interacting serine/threonine-protein kinase 2 CARD-carrying kinase CARD-containing IL-1 beta ICE-kinase CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase RIP-2 growth-inhibiting gene 30 receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase receptor-interacting protein 2 tyrosine-protein kinase RIPK2 CARD3 CARDIAK CCK GIG30 RICK RIP2 Click to show/hide the synonyms
Properties