Protein Name receptor interacting serine/threonine kinase 2
Organism Homo sapiens
Gene ID 8767
Gene Symbol

RIPK2

UniProt O43353 (RIPK2_HUMAN), A0A0S2Z4Z8 (A0A0S2Z4Z8_HUMAN)
Relationships Total Number of functionally related compound(s) : 90
Total Number of Articles : 89
Description

receptor interacting serine/threonine kinase 2

Gene Summary

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008]

synonyms
  • receptor-interacting serine/threonine-protein kinase 2
  • CARD-carrying kinase
  • CARD-containing IL-1 beta ICE-kinase
Click to show/hide the synonyms
Properties